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Journal and News Scan

Source: American Journal of Cardiology
Author(s): Costopoulos C, Latib A, Maisano F, Testa L, Bedogni F, Buchanan L, Naganuma T, Sticchi A, Sato K, Miyazaki T, Figini F, Giannini F, Taramasso M, Naim C, Carlino M, Chieffo A, Montorfano M, Alfieri O, Colombo A.
There have been some concerns about outcomes of TAVI in patients with bicuspid aortic valves (BAV). In this retrospective study, outcomes after TAVI in 21 patients with BAVs were compared with those in 447 patients with tricuspid aortic valves (TAV). Device success was lower and 30-day mortality was higher in BAV patients. There was no significant difference between groups in terms of 30-day composite safety end point, postprocedural aortic regurgitation or in 12-month cardiovascular mortality.
Source: Journal of Nuclear Medicine
Author(s): ZB Zeliadt, ET Loggers, CG Slatore, DH Au, PL Herbert, GJ Klein, LG Kessler, LM Backhus

During the period 1997-2009, nearly 3,000 military veterans with NSCLC were evaluated regarding the utility of PET in staging their cancers.  PET use increased in frequency during the study period from 9% to 91%.  PET reduced the chance of unnecessary surgery by nearly 50%. 

Source: Journal of Clinical Oncology
Author(s): G Sozzi, M Boeri, M Rossi, C Verri, P Suatoni, F Bravi, L Roz, D Conte, M Grassi, N Sverzellati, A Marchiano, E Negri, C La Vecchia, U Pastornio

In an effort to provide diagnostic information complementary to radiographic screening for lung cancer, the authors evaluated the diagnostic performance of plasma mRNA.  The mRNA signature classifier demonstrated 87% sensitivity and 81% specificity, with a negative predictive value of 99%.  In contrast, low dose CT had a sensitivity of 79% and a specificity of 81%.  Combining the mRNA signature classifier and low dose CT resulted in a 5-fold decrease in false positive findings based on CT alone.

Source: Annals of Thoracic Surgery
Author(s): Nathan M. Mollberg, Carrie Bennette, Eric Howell, Leah Backhus, Beth Devine, Mark K. Ferguson

LVI is thought to be an adverse prognostic indicator of survival in patients with NSCLC.  This review quantified the relationship of LVI and survival.  The unadjusted effect of LVI for recurrence-free survival was HR=3.63 and for overall survival was HR=2.38.  After adjustment for covarates, these HRs were 2.52 and 1.81, both highly significant. 

Author(s): list25
From plane crashes to lightning strikes these are the 25 things that are statistically most likely to kill you.
Source: Medscape
Author(s): Laird harrison
A new study suggests that delaying heart surgery may be associated with a high risk of adverse events or death in the period between dental surgery and a planned cardiac operation
Source: Thoracic Surgery News
Author(s): Bruce Jancin
Routine screening is warranted for the first-degree relatives of patients who present with thoracic aortic disease before age 60 years in the absence of predisposing conditions such as hypertension, Marfan syndrome, or bicuspid aortic valve, Dr. Elizabeth N. Robertson said at the American Heart Association scientific sessions. "We've shown that screening of first-degree relatives for familial thoracic aortic aneurysm disease is essential, as we detected an average of two additional affected individuals per initial patient
Author(s): Thessgiatro Giatroi Thessalonikis
This is an amazing video that actually shows live evidence of clot in the vein after harvesting ! Why are we all not doing this routinely after all vein harvest ? You must have a quick look at this
Source: Journal of the American Medical Association
Author(s): Christopher Vinden; Danielle M. Nash; Jagadish Rangrej; Salimah Z. Shariff; Stephanie N. Dixon; Arsh K. Jain; Amit X. Garg
The debate between surgeon sleep deprivation and performance continues. This study looked at complications from laparoscopoic cholecystectomies (n=94,183) in surgeons who operateed the night before and found no difference in outcomes. Although lap cholecystectomies don't translate to cardiothoracic surgery, some of the discussion points apply. Also, there is an excellent editorial accompanied the article written by Michael Zinner and Julie Ann Freischlag.
Source: Circulation
Author(s): Van Belle E, Juthier F, Susen S, Vincentelli A, Iung B, Dallongeville J, Eltchaninoff H, Laskar M, Leprince P, Lievre M, Banfi C, Auffray JL, Delhaye C, Donzeau-Gouge P, Chevreul K, Fajadet J, Leguerrier A, Prat A, Gilard M, Teiger E; for the FRANCE 2 Investigators.
In this study, the authors evaluate the relevance of post-procedural-aortic-regurgitation (AR) following transcatheter aortic valve replacement (TAVR) in patients included in the FRANCE 2 registry. They compare outcomes and risk factors for post-procedural AR in balloon expandable (BE) and self-expandable (SE) prosthesis. Not surprisingly, post-procedural AR was significantly more frequent in SE than in BE prosthesis. Post-procedural AR ≥2 was a predictor of 1-year mortality. Risk factors for post-procedural AR were identified for BE and SE prosthesis.