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Journal and News Scan
A prospective multicentre study analysed 532 patients with a first surgical procedure for pulmonary metastases of colorectal carcinoma. Complications arose in 16%, reoperations were necessary in 1% and mortality was 0.4%. Major lung resection and respiratory and/or cardiovascular co-morbidity were identified as independent risk factors, whereas a video-assisted approach was protective.
A consensus statement on video-assisted thoracoscopic lobectomy for patients with non-small-cell lung cancer has been issued by 50 international experts.
Carcinoid heart disease is a major cause of morbidity and mortality in patients with metastatic neuroendocrine tumours (NETs). Although cases of carcinoid syndrome and severe carcinoid heart disease requiring urgent intervention are well described, many patients with significant carcinoid heart disease may have insidious symptoms or even be asymptomatic. As haemodynamically significant carcinoid heart disease may be clinically silent, specific and individualised considerations must be made as to the most appropriate clinical criteria and time point at which surgical valve replacement should be undertaken in patients with carcinoid heart disease.
On March 20, 2014, a panel of the FDA gave unanimous approval for use of an ex-vivo perfusion system for improving the quality of explanted lungs prior to transplantation. If this recommendation is followed by the FDA, such devices could be used clinically under IRB protocols.