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January 10, 2015
The authors retrospectively analyzed pathologic response rates and their relation to the interval between completion of induction therapy and esophagectomy for esophageal cancer in 88 patients.  Complete response rates increased from 12.5% to 40.9% among quartiles as the interval increased from <45 days to >63 days.  There was no increase in mo
December 18, 2014
This randomized trial in New Zealand assigned smokers who wished to quit to either nicotrine replacement therapy or cytisine therapy.
December 10, 2014
This interesting article summarizes the evidence from clinical, radiologic and pathologic investigations that lung cancer, specifically adenocarcinoma, may metastasize through the airways, defined as discontinuous spread of cancer cells from the primary tumor through the airways to adjacent or distant lung parenchyma.
December 6, 2014
A hot topic at the recent meeting of the RSNA (Radiological Society of North America) was the implementation of LungRADS, a scoring system for categorizing lesions on CT, to be utilitized as part of CT screening for lung cancer.  Scans are assigned to one of 5 categories, ranging from incomplete to 4A (suspicious, follow-up or further testing warrant
December 3, 2014
This study explored recent patterns of surveillance imaging 4-8 mos after surgical treatment of early stage lung cancer using the SEER database.  Initial imaging consisted of CXR (60%), CT (25%) and PET (3%).  13% of patients received no imaging.  NCCN guidelines adherence for receipt of CT was 47%, but increased from 28% to 60% over the period of st
December 1, 2014
This video demonstrates a technique for a right video-assisted pneumonectomy.
November 30, 2014
A reexamination of data from the National Lung Screening Trial (NLST) with nodules above the 4mm, has been shown that increasing the nodule size threshold for a positive screen, substantially reduces the false-positive CT screenings rate and increase slightly the lung cancer missed or delayed but without affecting the survival.
November 24, 2014
This video demonstrates two helpful items for uniportal VATS lobectomy: a SILS Dissector and a MicroCutter.
November 24, 2014
Data from the Barrett's and Esophageal Adenocarcinoma Genetic Susceptibility Study were used to determine the relationship of a genetic risk score associated with obesity to cancer risk.  The risk score was not associated with GERD or smoking.  Cancer and Barrett's were strongly associated with increasing BMI.  The authors conlude that those with a g
November 24, 2014
Data from the National Lung Screening Trial (NLST) were examined by exploring different size thresholds for classifying CT screening scans as positive.  In the NLST, nearly two-thirds of nodules were 7mm in diameter or less.  Using a threshold of 5mm, the percentage of missed/delayed diagnosis and the likelihood of avoiding false positive findings we