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Esophagus

April 28, 2015
This video demonstrates the technical aspects of a full thickness laparoscopic intra-gastric resection of a symptomatic leiomyoma at the level of the gastro-esophageal junction.
February 13, 2015
This carefully prepared book is a wonderful compendium of scientific evidence regarding squamous cell cancer of the esophagus, written from a Japanese perspective.
January 29, 2015
There is growing recognition that hospital mortality is not an accurate metric for surgery-related mortality after cancer operations.  This article evaluated SEER data for 1-month mortality after cancer surgery in nearly 54,000 patients.  4.8% died within 1 month of surgery.  Favorable factors included being married, being insured, having an above-me
January 29, 2015
This meta-analysis evaluated 6 published studies involving over 71,000 cancer patients who experienced 2002 instances of cancer mortality.  Compared to patients with low fitness, those with high levels of cardiorespiratory fitness had a 50% reduction in their cancer mortality risk.
January 10, 2015
This study investigated repair methods for large hiatal hernias randomized to suture only vs absorbable mesh vs nonabsorbable mesh.  The design was randomized, double blind.  At 12 mos the recurrence rate was 21%, with no difference among the groups.  Postoperative symptoms were different among the groups, but these differences were judged to be of s
January 10, 2015
The authors retrospectively analyzed pathologic response rates and their relation to the interval between completion of induction therapy and esophagectomy for esophageal cancer in 88 patients.  Complete response rates increased from 12.5% to 40.9% among quartiles as the interval increased from <45 days to >63 days.  There was no increase in mo
November 24, 2014
Data from the Barrett's and Esophageal Adenocarcinoma Genetic Susceptibility Study were used to determine the relationship of a genetic risk score associated with obesity to cancer risk.  The risk score was not associated with GERD or smoking.  Cancer and Barrett's were strongly associated with increasing BMI.  The authors conlude that those with a g
November 20, 2014
Data from 20 observational studies including nearly 3000 pts were reviewed to assess the prevalence of pre-frailty/frailty and clinical outcomes in older cancer patients.  Frailty was identified in 42% and pre-frailty in 43% of patients.  Combined frailty was associated with increased all cause mortality (5-yr HR 1.57), postoperative mortality, and p
November 16, 2014
This retrospective study evaluated results of transthoracic (TTE) vs transhiatal (THE) esophagectomy in patients with squamous cell cancer and adenocarcinoma from two high volume centers.
November 16, 2014
This article systematically reviewed the impact of surgical adverse events (SAEs) on quality of life after major GI surgery.  The mean difference in QOL between pts with and without SAEs was highest for esophagectomy (0.14; scale 0 to 1), while results for antireflux surgery were mixed. 

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