ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Lung

September 27, 2015
One fourth of lung cancer patients are never smokers, consisting of 53% of women with lung cancer and 15% of men; the majority of these are adenocarcinomas. Estrogens interact with two types of receptors, ERα and ERβ, and may play a role in the development of lung cancer.
September 23, 2015
This video demonstrates a thoracoscopic left upper lobectomy for persistent hemoptysis from a left upper lobe PAVM, despite multiple embolizations.
September 21, 2015
In this video, the authors demonstrate their first robotic left pneumonectomy for a pT2N1 neoplasm.
September 20, 2015
A large retrospective study comparing 117618 patients from the National Cancer Database with Stage I NSCLC. 111731 received surgery, 5887 received SBRT. In a propensity managed comparison, those undergoing surgery had increased overall survival.
September 16, 2015
Outcomes of the California Cancer Registry for patients undergoing resection for Stage I NSCLC were evaluated according to Commission on Cancer (CoC) accreditation status and lung resection procedure volume.  High volume hospitals (>50 annually) had better survival compared to medium (20-50 annually; HR 1.23) and low volume (<20 annually; 1.77)
September 12, 2015
This randomized trial compared induction therapy for pathologically-proven N2/IIIA NSCLC with 3 cycles of cisplatinum and docetaxel chemotherapy alone to chemotherapy combined with 44 Gy of radiation therapy.  232 pts in 23 centers were enrolled over a 12 year period.  No differences were identified in the chemotherapy vs chemoradiotherapy groups for
August 26, 2015
Investigators from Stanford developed a nine-gene expression predictor for survival outcome in early-stage nonsquamous NSCLC. They developed and validated a quantitative real-time polymerase chain reaction assay easily applicable to routinely obtained paraffin-embedded tumor specimens.
August 22, 2015
This comprehensive review outlines changes in the WHO classification of lung tumors, chagnes that will affect our clinical practice in the near future.
August 20, 2015
Thus far, only 3 randomized controlled trials (RCTs) have compared stereotactive ablative radiotherapy (SABR) versus surgery in patients with early stage NSCLC (STARS trial, ROSEL trial, and ACOSOG Z4099 trial). Unfortunately all 3 were unable to meet the accrual goals and were closed early.
August 20, 2015
This is an invited commentary on the article by Chang and colleagues (Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials).

Pages