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Testing Epinephrine for Out-of-Hospital Cardiac Arrest

Friday, August 31, 2018

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Source Name: The New England Journal of Medicine


Clifton W. Callaway, Michael W. Donnino

A balanced editorial discussing the relevant RCT from Britain. The esteemed authors are correct to highlight the overall discouraging survival from out-of-hospital cardiac arrest WITHOUT NEUROLOGICAL DEFICIT. What does need to be done to improve a 3% acceptable outcome? The 'non-superiority' of adrenaline (epinephrine) is, under the devastating primary outcome, a finding of secondary importance for the general public.  

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