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Journal and News Scan
This meta-analysis of 18 randomized trials investigated the risk of infection related to blood transfusions given according to liberal or restrictive criteria. The restrictive strategy (Hgb <7) was associated with an 18% reduction in the risk of serious infection (11.8% vs 16.9%). The effects were most pronounced in patients with sepsis and in those undergoing orthopedic surgery. No difference was evident among patients with heart disease, critical illness, or GI bleeding.
In this observational study, the utility of decellularized allogeneic pulmonary artery patches for pulmonary arterioplasty was evaluated in 108 patients. No device failures or adverse events were detected. An historical comparison cohort in whom conventional materials were used experienced a 14% failure rate.