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Lung Cancer - Other

February 6, 2015
The Centers for Medicare and Medicaid Services (CMS) announced on February 5, 2015, that CT lung cancer screening will be a covered service.  This long awaited decision followed the preliminary announcement in November 2014.  After a period of comment, the coverage ages were expanded to include patients 55-77 years old.  The process mandates maintena
February 3, 2015
This consensus statement from the European Neuroendocrine Society is based on extensive bibliographic searches and systematic review.  Surgery is the mainstay of therapy for most tumors, and includes resection of metastases when this can be accomplished in a curative manner.  Somatostatin analogues are considered first line therapy for unresectable c
January 29, 2015
There is growing recognition that hospital mortality is not an accurate metric for surgery-related mortality after cancer operations.  This article evaluated SEER data for 1-month mortality after cancer surgery in nearly 54,000 patients.  4.8% died within 1 month of surgery.  Favorable factors included being married, being insured, having an above-me
January 29, 2015
This meta-analysis evaluated 6 published studies involving over 71,000 cancer patients who experienced 2002 instances of cancer mortality.  Compared to patients with low fitness, those with high levels of cardiorespiratory fitness had a 50% reduction in their cancer mortality risk.
December 18, 2014
This randomized trial in New Zealand assigned smokers who wished to quit to either nicotrine replacement therapy or cytisine therapy.
December 10, 2014
This interesting article summarizes the evidence from clinical, radiologic and pathologic investigations that lung cancer, specifically adenocarcinoma, may metastasize through the airways, defined as discontinuous spread of cancer cells from the primary tumor through the airways to adjacent or distant lung parenchyma.
December 6, 2014
A hot topic at the recent meeting of the RSNA (Radiological Society of North America) was the implementation of LungRADS, a scoring system for categorizing lesions on CT, to be utilitized as part of CT screening for lung cancer.  Scans are assigned to one of 5 categories, ranging from incomplete to 4A (suspicious, follow-up or further testing warrant
December 3, 2014
This study explored recent patterns of surveillance imaging 4-8 mos after surgical treatment of early stage lung cancer using the SEER database.  Initial imaging consisted of CXR (60%), CT (25%) and PET (3%).  13% of patients received no imaging.  NCCN guidelines adherence for receipt of CT was 47%, but increased from 28% to 60% over the period of st
November 30, 2014
A reexamination of data from the National Lung Screening Trial (NLST) with nodules above the 4mm, has been shown that increasing the nodule size threshold for a positive screen, substantially reduces the false-positive CT screenings rate and increase slightly the lung cancer missed or delayed but without affecting the survival.
November 24, 2014
Data from the National Lung Screening Trial (NLST) were examined by exploring different size thresholds for classifying CT screening scans as positive.  In the NLST, nearly two-thirds of nodules were 7mm in diameter or less.  Using a threshold of 5mm, the percentage of missed/delayed diagnosis and the likelihood of avoiding false positive findings we