The authors reviewed patients with small resected stage I lung adenocarcinoma to determine the frequency of tumor cells spreading through airway spaces (STAS) and their relationship to recurrent cancer. Nearly 40% of patients had tumor cells in the airways beyond the edge of the main tumor. In patients undergoing parenchymal-sparing operations, the
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Lung Cancer - Other
March 16, 2015
This Netherlands population-based study followed causes of death in patients with NSCLC diagnosed 1989-2008, including more than 72,000 patients. For those with localized disease, lung cancer was the cause of death in 80-85% for years 0-3, 60-75% for years 4-6, and remained the cause of death for more than 30% thereafter. After 6 years CAD and COPD
March 16, 2015
The authors describe results of initial bronchoscopy therapy (IBT) for endobronchial carcinoids aimed at relieving obstruction, accurate subtyping, and potentially complete eradication. After a minimum follow-up of 5 years, 42% of patients were spared surgical therapy, having had no evidence of local or distant recurrence (42/83 with typical histolo
February 21, 2015
A survey involving the general public identified opinions regarding lung cancer. Most felt it was related to smoking and lifestyle, was a serious cancer, and involved major treatments. The participants underestimated cure rates for early stage disease (52% survival) and overestimated overall survival (32% survival).
February 16, 2015
Usually patients with prior cancer are excluded in lung cancer trials, but the impact on survival in lung cancer is not known. In a cohort of 102929 patients older than 65 with stage IV lung cancer, a propensity score analysis were performed and found that patients with prior cancer had better survival (all-cause and lung cancer-specific).
February 16, 2015
This trial randomized 61 pts to a program of endurance and strength training or no training beginning 5-7 weeks after lung resection for cancer and lasting 20 weeks. Compared to controls, treatment group patients demonstrated significant improvements in peak O2 uptake, DLCO, leg and arm strength, muscle mass, and QOL.
February 6, 2015
The Centers for Medicare and Medicaid Services (CMS) announced on February 5, 2015, that CT lung cancer screening will be a covered service. This long awaited decision followed the preliminary announcement in November 2014. After a period of comment, the coverage ages were expanded to include patients 55-77 years old. The process mandates maintena
February 3, 2015
This consensus statement from the European Neuroendocrine Society is based on extensive bibliographic searches and systematic review. Surgery is the mainstay of therapy for most tumors, and includes resection of metastases when this can be accomplished in a curative manner. Somatostatin analogues are considered first line therapy for unresectable c
January 29, 2015
There is growing recognition that hospital mortality is not an accurate metric for surgery-related mortality after cancer operations. This article evaluated SEER data for 1-month mortality after cancer surgery in nearly 54,000 patients. 4.8% died within 1 month of surgery. Favorable factors included being married, being insured, having an above-me
January 29, 2015
This meta-analysis evaluated 6 published studies involving over 71,000 cancer patients who experienced 2002 instances of cancer mortality. Compared to patients with low fitness, those with high levels of cardiorespiratory fitness had a 50% reduction in their cancer mortality risk.