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Lung Cancer - Other

November 8, 2017
This multicenter retrospective study sought to assess the utility of PET in the diagnosis of pulmonary nodules.  It emphasized the inclusion of patient cohorts from different geographic regions and who underwent PET for different indications such as lung cancer screening or surgical evaluation.  Among 1188 patients the positive predicted value was 86
October 24, 2017
Surgical treatment of metastatic disease, particularly lung cancer metastases, is often controversial.  This article reviews the literature on therapeutic surgical interventions, and comments on diagnostic, palliative, and consolidation roles for surgery in patients with stage IV NSCLC.
October 24, 2017
A useful reminder of the substantial progress that has been made and the continuing challenges that we face in fighting this terrible disease.
October 2, 2017
Researchers used  a nanomaterial sensor array and pattern recognition statistical techniques to evaluate exhaled breath samples from patients with suspicious lesions on imaging.  A total of  119 patients were included, of whom 30 had benign lesions.  In cancer patients, the accuracy of discriminating EGFR mutations from wild-type EGFR was 83
October 2, 2017
The authors demonstrated substantial concordance between sequencing of 39 genes in a liquid assay and routine diagnostic testing in tissue in 82 patients.  Agreement was 98%, and the primary reason for failure was low levels of circulating DNA in the plasma.  Sensitivity was 70%, and specificity was 100%.  The system offers accurate identification of
August 2, 2017
This retrospective study of the association of BMI to long-term survival after resection of NSCLC identified BMI > 30kg/m2 as an independent predictor of survival.  In a propensity score matched set, patients with BMI >30 had better survival than those with a BMI of 25 (p=0.003).   The reason for this relationship remains to be elucidated.
August 2, 2017
This is an excellent summary of progress during the past year in all aspects of lung cancer, from prevention/detection through molecular therapies and future perspectives.  Each section is written by a handful of international experts. 
February 24, 2016
Routine use of PET scans to follow up asymptomatic patients do not affect survival, according to this retrospective analysis of a cohort of 97,152 lung cancer and 4,446 esophageal cancer patients. They compared high and low level of use of PET centers, and found no differences in two-year survival. 
August 11, 2015
This single institution retrospective study evaluated the relationship of adenocarcinoma subtype to long-term survival after resection of stage I lung cancer.  Patients with solid-predominant tumors experienced recurrences earlier, more often in distant sites, and more often in multiple locations.  This subtype was also independently associated with
July 16, 2015
In order to improve the diagnostic accuracy of bronchoscopy for lung cancer, epithelial cells were collected from normal appearing mucosa in the mainstem bronchus of patients suspected of having lung cancer during diagnostic bronchoscopy.  The samples were evaluated with a gene expression classifier.  43% of the standard examinations were nondiagnost

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