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Lung Cancer - Other

October 15, 2014
Using a data set of over 76,000 women from the Women's Health Initiative Observational Study, the effects of active and passive smoking on cancer were evaluated.  Lung cancer incidence was highest among active smokers (HR 13.44) and was also high among prior smokers (HR 4.20).  A prolonged exposure (>30 yr) to passive smoking in the household also
October 14, 2014
Lung cancer cases 2000-2013 in the UK Health Improvement Network were evaluated for factors associated with early death (within 90 days of diagnosis) vs later death.  Risk factors for early death included male sex, older age, current smoking, social deprivation, and rural location.  Those experiencing early death saw their primary care physicians mor
September 25, 2014
Costs of lung cancer screening were determined for individuals with a 2% or greater risk of lung cancer over 3 years for 2059 subjects participating in the Pan-Canadian Early Detection of Lung Cancer Study.  During the first 18 mos of screening the per-person cost was $453.  Surgical therapy cost $33,344 over 2 years compared to costs of treating adv
September 25, 2014
A model for predicting lung cancer in patients with suspicious lung nodules (TREAT) was developed using single institutional data (Vanderbilt), validated using data from another institution, and compared to the Mayo Clinic predictive model.  The model accuracy was 87% in the development cohort and 89% in the validation cohort, compared to 80% in the
September 25, 2014
This meta-analysis of 70 studies evaluated the utility of PET in assessing over 8,511 lung nodules, comparing regions in which infectious lung disease is endemic to other regions.  Specificity was lower in regions with endemic infectious diseases, 61% vs 77%.  Overall, the accuracy of PET was extremely heterogeneous.
September 5, 2014
Screening for lung cancer with low-dose CT has been shown to save lives, but few people who qualify for screening actually receive it.  This study examined the use of the electronic medical record to identify pts at risk due to a smoking history.  Prior to initiation, the annualized rate of referral for screening was 16 pts.  After initiation the ann
September 5, 2014
This single institution study tracked outcomes of a unique lung cancer survivorship program facilitated by a nurse practitioner who was trained in survivorship care.  The nurse took over follow-up care of early stage patients who survived disease-free for more than 1 year.  92% of eligible pts received follow-up care by the nurse.  The program identi
July 29, 2014
Records of nearly 24,000 Australian patients with NSCLC were evaluated to determine the relationship between distance to the nearest speciality hospital (NASH) and survival.  Increasing distance from a NASH was associated with decreasing likelihood of admission to a NASH and decreasing likelihood of lung cancer resection, resulting in an increasing h
July 26, 2014
Outcomes of lung adenocarcinoma classified according to the new IASLC/ATS/ERS system were evaluated in this retrospective single-institution study involving 573 pts who underwent surgical treatment.  Histologic patterns were associated with sex and tumor TNM factors.  Recurrence was higher in micropapillary and solid-predominant cancers.  These subty
July 8, 2014
This is an interesting opinion piece about misplaced fears on the part of physicians and patients/families regarding the dangers of radiation exposure as part of diagnostic imaging.