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Journal and News Scan

Source: The New England Journal Of Medicine
Author(s): Helio P. Guimarães, Renato D. Lopes, Pedro G.M. de Barros e Silva, Idelzuita L. Liporace, Roney O. Sampaio, Flávio Tarasoutchi, Conrado R. Hoffmann-Filho, Rodrigo de Lemos Soares Patriota, Tiago L.L. Diana Lamprea, Dalton B. ., Fernando A. Atik, Fabio S. Silveira, ., Fabio R. Farias, Diogo O. Barreto, Adail P. Almeida, Alexandre C. Zilli, João D. de Souza Neto, Margaret A. Cavalcante, Fernando A.M.S. Figueira, Flávia C.S. Kojima, Lucas Damiani, Renato H.N. Santos, Nanci Valeis, Viviane B. Campos, Jose F.K. Saraiva, Francisco H. Fonseca, Ibraim M. Pinto, Carlos C. Magalhães, Joao F.M. Ferreira, John H. Alexander, Ricardo Pavanello, Alexandre B. Cavalcanti, Otavio Berwanger, for the RIVER Trial Investigators

A large RCT with results somewhat supportive of considering a NOAC in the place of warfarin for post operative surgical patients. The study will be weighed against healthcare economical aspects. One question will arise:  Why,  if there was a subgroup ( the cohort had an average age below 60 years) eceiving lifelong warfarin or equivalent anticoagulation prior to surgery, they did not have a mechanical prosthesis?  It is of course possible that local financial constrains impede access to such devices, and bioprostheses were more affordable.  

Source: The Journal of Thoracic and Cardiovascular Surgery
Author(s): Hughes GC

A relatively recent, open-access, brief viewpoint on the utility of screening for thoracic aortic pathologies. Although the negative opinion expressed by the author may not be universally accepted, a debate fuelled by data and especially patient-centered cerebrospinal outcomes will certainly be of benefit; evem more so with the spreading of metrics for prediction of acute complications of aortic disease.

Source: Journal of Cardiothoracic and Vascular Anesthesia
Author(s): Jason Z. Qua, Lee-Wei Kaoa, Jennifer E. Smitha, Alexander Kuoa, Albert Xueb, Manoj H. Iyerc, Michael K. Essandohc, and Adam A. Dalia

This is a comprehensive review of current strategies for monitoring and protection of the brain during aortic arch surgery under hypothermic circulatory arrest. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Lucas Hoyos Mejía, Alejandra Romero Román, Mariana Gil Barturen, Maria del Mar Córdoba Pelaez, José Luis Campo-Cañaveral de la Cruz, José Manuel Naranjo, Silvana Crolwey Carrasco, Shin Tanaka, Alvaro Sánchez Calle, Andrés Varela de Ugarte, David Gómez de Antonio

Hoyos Mejia et al. present a single center report regarding the outcome of thoracic surgery during the COVID-19 pandemic. They recorded a significant reduction in thoracic surgical cases. They observed five cases of coronarvirus infection in 101 surgical patients within 14 days after surgery. Two of these patients needed inpatient treatment and none died due to the infection. They conclude that it is safe to perform selected surgical procedures during the pandemic if managed properly.

Source: The Annals of Thoracic Surgery
Author(s): E. Hope Weissler, MD, Soraya L. Voigt, MD, Vignesh Raman, MD, Oliver Jawitz, MD, Julie Doberne, MD, PhD, Jatin Anand, MD, Ryan Plichta, MD, Jeffrey G. Gaca, MD, Richard L. McCann, MD, and G. Chad Hughes, MD

This study evaluated preoperative cerebrospinal fluid drainage (CSFD) In patients undergoing isolated descending TEVAR with or without arch involvement (+/− arch TEVAR).

Source: Frontiers in Oncology
Author(s): Rilan Bai, Lingyu Li, Xiao Chen, Naifei Chen, Wei Song , Jiuwei Cui*

A scholarly and sober narrative review on , as the authors state,  a ' hot topic' that is already being debated in Multidisciplinary Meetings and Lung Cnacer Boards.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Philipp Angleitner, Aleksa Matic, Alexandra Kaider, Kamen Dimitrov, Sigrid Sandner, Dominik Wiedemann, Julia Riebandt, Thomas Schlöglhofer, Günther Laufer, Daniel Zimpfer

Philipp Angleitner et al. present a retrospective study regarding incidence and outcome of bloodstream infections in LVAD patients. The incidence of bloodstream infections is 32.1% within the first year. This event was associated with increased risk of death and stroke. Risk factors of bloodstream infections were identified as lower albumin and ECMO/IABP prior to LVAD implantation.

Source: The Annals of Thoracic Surgery
Author(s): Danielle O’Hara, BS, Allison McLarty, MD, Erick Sun, BA, Shinobu Itagaki, MS, MD, Henry Tannous, MD, Danny Chu, MD, Natalia Egorova, PhD, and Joanna Chikwe, MD

The authors used The Society of Thoracic Surgeons Database to evaluate cerebral perfusion strategies for type A aortic dissection.

Source: The New England Journal of Medicine
Author(s): John R. Teerlink, Rafael Diaz, G. Michael Felker, John J.V. McMurray, Marco Metra, Scott D. Solomon, Kirkwood F. Adams, Inder Anand, Alexandra Arias-Mendoza, Tor Biering-Sørensen, Michael Böhm, Diana Bonderman, John G.F. Cleland, Ramon Corbalan, Maria G. Crespo-Leiro, Ulf Dahlström, Luis E. Echeverria, James C. Fang, Gerasimos Filippatos, Cândida Fonseca, Eva Goncalvesova, Assen R. Goudev, Jonathan G. Howlett, David E. Lanfear, Jing Li, Mayanna Lund, Peter Macdonald, Viacheslav Mareev, Shin-ichi Momomura, Eileen O’Meara, Alexander Parkhomenko, Piotr Ponikowski, Felix J.A. Ramires, Pranas Serpytis, Karen Sliwa, , Jindrich Spinar, Thomas M. Suter, Janos Tomcsanyi, Hans Vandekerckhove, Dragos Vinereanu, Adriaan A. Voors, Mehmet B. Yilmaz, Faiez Zannad, Lucie Sharpsten, Jason C. Legg, Claire Varin, Narimon Honarpour, Siddique A. Abbasi, Fady I. Malik, Christopher E. Kurtz for the GALACTIC-HF Investigators

A latge RCT of the first myosin inhibitor in severe chronic heart failure: somewhat difficult to interpret results, as deaths were slightly higher in the intervention group while there was no 'significant' benefit in cardiovascular deaths. The authors discuss the possibility of benefit in lower ejection fractions and proceed to discuss and present subgroups in an effort to glean some granularity in indications for omecamtiv mecarbil.

Author(s): Mario Castillo-Sang, Tom C. Nguyen, Rochus K. Voeller

This free online course provides a series of step-wise presentations for developing a minimally invasive valve program with contributions from experts in the fielid.