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Journal and News Scan

Source: DG News
Author(s): Lorraine L. Janeczko after Phillip M. King et al.

Will await the full paper to test the titular preliminary assertion. 

Source: News from around the web.
Author(s): Emily Robinson

Patient Care and General Interest

Saturday, September 29 is World Heart Day! This year’s theme is “My Heart, Your Heart.”

Gerald D. Buckberg, MD, a renowned heart surgeon who made a major contribution in the field of myocardial protection, recently passed away.

Team Heart, a group of medical volunteers, visits Rwanda once a year to perform life-saving valve replacement procedures caused by rheumatic heart disease, which is prevalent in many African and Asian countries.

An atrial fibrillation procedure performed on a keen Hong Kong-based marathon runner saved him from a life-threatening abnormal heart rhythm and gave him renewed energy when training.



Data presented at the recent TCT 2018 conference indicates that patients with severe symptomatic aortic stenosis and high risk of operative mortality who underwent TAVR had similar 5-year survival and stroke rates compared with those who underwent SAVR.

A study published in Pediatric Research indicates that neonates with congenital heart disease tend to have enlarged kidneys.

The BMI journal Heart has published research suggesting a link between mitral valve prolapse – a common condition – and sudden cardiac death.

Source: The Annals of Thoracic Surgery
Author(s): Gabie K.B. Ong, Richard K. Freeman, Anthony J. Ascioti, Raja S. Mahidhara, Vijay Nuthakki, Megan Dake, Daryl Eckstein

This single institution summary of treatment of failed stenting for esophageal perforation included 26 patients over an eight year period. Management included primary closure, esophagectomy, and observation. The overall prognosis was very good, supporting the use of stents as initial therapy for esophageal perforation in appropriate patients.

Source: Annals of Surgery
Author(s): McMurry TL, Stukenborg GJ, Kessler LG, Colditz GA, Wong ML, Francescatti AB, Jones DR, Schumacher JR, Greenberg CC, Chang GJ, Winchester DP, McKellar DP, Kozower BD

Using the National Cancer Database, the effect of the timing of computed tomography (CT) surveillance after resection of non-small cell lung cancer on survival was investigated.  Survival was similar for patients undergoing CTs every three months or every six months compared to those undergoing annual surveillance CTs.  More frequent imaging also had no impact on survival after recurrence.

Source: The Annals of Thoracic Surgery
Author(s): Seth B. Krantz, John A. Howington, Douglas E. Wood, Ki Wan Kim, Andrzej S. Kosinski, Morgan L. Cox, Sunghee Kim, Michael S. Mulligan, Farhood Farjah

Data in the STS Database indicate that invasive mediastinal staging is underused in patients undergoing resection for non-small cell lung cancer, and that the pattern of use varies widely among the participants. Use of guidelines outlining indications for invasive mediastinal staging should be encouraged.

Source: The Annals of Thoracic Surgery
Author(s): Leah M. Backhus, Beatty E. Fann, Dawn S. Hui, David T. Cooke, Kathleen S. Berfield, Susan D. Moffatt-Bruce

This objective, well-researched, and well presented article summarizes the importance of gender inclusion in cardiothoracic surgery as a means for improving institutional culture, patient safety, patient outcomes, and gender equality.

Source: International Association for the Study of Lung Cancer 19th World Conference on Lung Cancer
Author(s): Fred R. Hirsch

A seismic shift occurred today when the NELSON screening trial results were presented at the IASLC 19th World Conference on Lung Cancer (#WCLC2018). Hear from the CEO, Dr. Fred R. Hirsch, as he comments on these results. Men have a 24% survival advantage in the screening programme. This is a very large shift to earlier stage cancer detection. There can be no doubt that lung cancer screening is a lifesaving intervention in lung cancer.

Source: Annals of Cardiothoracic Surgery
Author(s): Mohamed Rahouma, Ahmed Abouarab, Antonino Di Franco, Jeremy R. Leonard, Christopher Lau, Mohamed Kamel, Lucas B. Ohmes, Leonard N. Girardi, Mario Gaudino

Meta-analysis of composite death/myocardial infarction/stroke/repeat revascularization outcome in 4700 patients across six randomized controlled trials is presented. Percutaneous coronary intervention was associated with a higher risk of the composite outcome in all SYNTAX score tertiles as well as increased risk of repeat revascularization. Additionally, no difference was shown between bare metal stent and drug eluting stents on a sub-group analysis.

Source: The New England Journal of Medicine
Author(s): Gregg W. Stone, JoAnn Lindenfeld, William T. Abraham, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Paul A. Grayburn, Michael Rinaldi, Samir R. Kapadia, Vivek Rajagopal, Ian J. Sarembock, Andreas Brieke, Steven O. Marx, David J. Cohen, Neil J. Weissman, and Michael J. Mack for the COAPT Investigators

This multicenter study evaluated the efficacy of medical therapy plus transcatheter valve repair (MitraClip) to medical therapy alone for heart failure accompanied by secondary moderate to severe mitral regurgitation. The device group experienced significantly fewer hospitalizations and lower mortality at 24 months follow-up. 

Source: The New England Journal of Medicine
Author(s): Scott J. Antonia, Augusto Villegas, Davey Daniel, David Vicente, Shuji Murakami, Rina Hui, Takayasu Kurata, Alberto Chiappori, Ki H. Lee, Maike de Wit, Byoung C. Cho, Maryam Bourhaba, Xavier Quantin, Takaaki Tokito, Tarek Mekhail, David Planchard, Young-Chul Kim, Christos S. Karapetis, Sandrine Hiret, Gyula Ostoros, Kaoru Kubota, Jhanelle E. Gray, Luis Paz-Ares, Javier de Castro Carpeño, Corinne Faivre-Finn, Martin Reck, Johan Vansteenkiste, David R. Spigel, Catherine Wadsworth, Giovanni Melillo, Maria Taboada, Phillip A. Dennis, Mustafa Özgüroğlu for the PACIFIC Investigators

This comprises the eagerly anticipated summary of the second primary endpoint of the PACIFIC trial of Durvalumab vs placebo in patients who completed CT/RT without progression for unresectable stage III NSCLC. Durvalumab significantly improved overall survival, progression free survival, and time to distant metastasis or death. No new safety concerns were raised.