ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Journal and News Scan

Source: The Journal of Thoracic and Cardiovascular Surgery
Author(s): Expert Consensus Panel, Biniam Kidane, Matthew Bott, Jonathan Spicer, Leah Backhus, Jamie Chaft, Neel Chudgar, Yolonda Colson, Thomas A. D'Amico, Elizabeth David, Jay Lee, Sara Najmeh, Boris Sepesi, Catherine Shu, Jeffrey Yang, Scott Swanson, Brendon Stiles

A new expert consensus on diagnosis, staging, and therapy for early-stage non-small cell lung cancer patients has been released. The experts recommend CT and PET imaging as a necessary part of the diagnosis and staging phase. Recommendations for chemotherapy, radiotherapy, and adjuvant systemic therapy before and after lung resection are also explained in this report. Overall, treatment paradigms have shifted significantly over the past few years and surgeons must be knowledgeable about different treatment options. 

Source: JAMA
Author(s): Enoch F. Akowuah Rebecca H. Maier, Helen C. Hancock, Ehsan Kharatikoopaei, Luke Vale, Cristina Fernandez-Garcia, Emmanuel Ogundimu, Janelle Wagnild, Ayesha Mathias, Zoe Walmsley, Nicola Howe, Adetayo Kasim, Richard Graham,Gavin J. Murphy, Joseph Zacharias, for the UK Mini Mitral Trial Investigators

This is a groundbreaking article that, for the first time, compares port access mitral surgery with sternotomy in a randomized multicenter trial. It demonstrates benefits for surgery through a minimal access route and, most importantly, that it is as safe as open surgery. Finally, it demonstrates that expert surgeons are required, whatever the access, to maximize the repair rate for patients.

While this full report is behind a paywall, a detailed abstract is included through the link above.

Source: Middle East Monitor
Author(s): MEMO Staff

Through the Palestine Children’s Relief Fund (PCRF), a group of Italian doctors and nurses traveled to the Gaza Strip to perform cardiac surgery on a group of ten children with congenital heart disease. Since advanced surgical procedures are not readily accessible in the occupied area because of lack of resources and a travel ban, the surgical team was crucial for treating these urgent cases and training local medical professionals.

Source: The Annals of Thoracic Surgery
Author(s): Cheung, Iliopoulos, et. Al.

This analysis of 279 neonates with pulmonary atresia and intact ventricular septum who underwent surgical or catheter intervention between 2009 and 2019 in nineteen centers showed that seventy-nine (28 percent) underwent right ventricular decompression, 151 (54 percent) underwent systemic-to-pulmonary shunt or ductal shunt only, thirty-six (13 percent) underwent both, and eleven (4 percent) received transplants. Major adverse events—including in-hospital mortality (8 percent), cardiopulmonary resuscitation (13 percent), stroke (6 percent), and mechanical circulatory support (13 percent)—were reported in fifty-seven patients (20 percent). Lower weight and the presence of two major coronary stenoses predicted major adverse events, and the authors recommend vigilance in procedural planning in patients with these risk factors.

Source: Gastroenterology Advisor
Author(s): Gastroenterology Advisor Contributing Writer

A study in the United States found that disparities regarding race, socioeconomic status, and rural location result in lack of access to a thoracic surgeon for an esophagectomy. Patients in the study underwent elective esophagectomy for esophageal or gastric cardia cancer, Barrett esophagus, or achalasia. While the proportion of esophagectomies performed by thoracic surgeons increased over the four-year study period, demographic differences persisted. Patients who were uninsured, identified as non-white, received care in a rural setting, or had metastatic cancer were significantly less likely to have their esophagectomy performed by a thoracic surgeon.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Koizumi S, Inoue Y, Shinzato K, Yokawa K, Kasai M, Masada K, Seike Y, Sasaki H, Matsuda H

The authors investigated the outcomes of thoracic endovascular aortic repair for retrograde Stanford type A acute aortic dissection (R-AAAD) at their institution. The early- and mid-term outcomes of thoracic endovascular aortic repair for R-AAAD in nineteen patients were satisfactory, but long-term follow-up is needed. The indications for such repair have been expanded to include low-risk and emergency cases at the authors’ institute.

Source: The Journal of Heart and Lung Transplantation
Author(s): Diyar Saeed, David Feldman, Aly El Banayosy, Emma Birks, Elizabeth Blume, Jennifer Cowger, et al

The first official guidelines for implantable mechanical circulatory support (MCS) were published in 2013 by the International Society for Heart and Lung Transplantation (ISHLT). Ten years later, because of substantial advancements in the MCS field, much of the original report is no longer clinically relevant, so ISHLT commissioned a ten-year update. Like the 2013 MCS guidelines, the 2023 update are organized into individual task forces covering preoperative, intraoperative, and postoperative management of MCS patients treated with implantable left ventricular assist devices (LVADs), including four additional task forces, for a total of nine. With those additions, ISHLT says this 2023 guideline document is the most comprehensive resource guiding the management of patients with durable mechanical circulatory support (DMCS).

The nine task forces are as follows:

  1. Selection of candidates for durable mechanical circulatory support (DMCS) and risk management before implantation for fixed comorbidities.
  2.  Patient optimization, consent, and appropriate timing for MCS: Modifiable risk management before implantation.
  3. Intraoperative and immediate postoperative management
  4.  Inpatient management of patients with DMCS.
  5. Outpatient management of the mechanical circulatory support device recipient.
  6. VAD in adults with congenital heart disease.
  7. Evaluation for recovery.
  8. Biventricular assist devices and total artificial heart specifications.
  9. Center quality metrics, outcomes, volume, and staffing.
Source: European Journal of Cardio-Thoracic Surgery
Author(s): Berger T, Chikvatia S, Siepe M, Kondov S, Meissl D, Gottardi R, Rylski B, Czerny M & Kreibich M
The authors examined the safety of combining aortic root replacement with frozen elephant trunk (FET) total arch replacement. Outcomes were similar between the FET alone and FET with aortic root replacement groups. Adding aortic root replacement was not associated with increased mortality and there was no difference in overall survival between the groups. Although concomitant root replacement lengthens the operation time, it does not appear to increase risk in an experienced centre with high volumes.
Source: The New England Journal of Medicine
Author(s): COAPT Investigators

This five-year follow-up of a large randomized controlled clinical trial on outcomes after transcatheter edge-to-edge repair of severe mitral regurgitation, as compared with outcomes after maximal doses of guideline-directed medical therapy alone, suggests superiority of the transcatheter 'Alfieri' (Mitra-clip) repair over BMT.

It will be interesting to juxtapose transcatheter to surgical repair, especially over a longer period. It's worth noting that more than one in ten recipients suffered device-related complications.

Source: Healio
Author(s): Regina Schaffer

A study found that patients who underwent a second TAVR procedure were no more likely to experience adverse outcomes than those who have only undergone one TAVR. Because TAVR patients are expanding into younger populations, the analysis of registry data is important in informing decision making among these patients, who are more likely to need a second TAVR in their lifetimes.

Pages