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Journal and News Scan

Source: JAMA Network Open
Author(s): Elisabeth M. Schaffer, Rebecca Giok Sim Su, Junxing Chay, Eric A. Finkelstein

This article examined patients in Singapore who were ineligible for transplantation and evaluated the cost-effectiveness of left ventricular assist device (LVAD) use compared to optimal medical therapy. The authors found that LVAD use resulted in higher quality-adjusted survival for the transplant-ineligible population; however, its value varied based on inotrope dependance. Patients who were inotrope dependent were found to have more cost-effective use of LVADs compared to those who were inotrope independent. The authors suggest that this information could be utilized to adjust device prices nationally as part of public health initiatives. 

Source: Interdisciplinary Cardiovascular and Thoracic Surgery
Author(s): Beatrice Leonardi, Stefano Forte, Antonio Marella, Francesco Panini D’Alba, Giuseppe Vicario, Grazia Bergameo, Francesca Capasso, Francesco Leone, Noemi Maria Giorgiano, Davide Gerardo Pica, Emanuele Martorana, Riccardo Villa, Maria Marvulli, Riccardo Monti, Gaetana Messina, Francesco Ferrigno, Marco Mosella, Paolo Chiodini, Giovanni Vicidomini, Alfonso Fiorelli

This retrospective single-center study evaluated the impact of 3D airway reconstruction on planning tracheobronchial stent insertion for malignant central airway obstruction (MCAO) in 136 patients from 2012 to 2024. Forty patients underwent stenting with preoperative 3D reconstruction, while 96 had standard planning.   

Both groups achieved a 96 percent airway patency restoration rate. However, the 3D reconstruction group showed a significant 17 percent reduction in operative time (median 40 minutes vs. 48 minutes; p=0.03) and a lower stent migration rate (5 percent vs. 17 percent; p=0.04). There were no differences in 30- or 90-day mortality. The 3D models, generated using open-source software from high-resolution CT scans, allowed detailed visualization of stenosis morphology and virtual endoscopy, facilitating optimal stent selection and placement. The observed improvements in efficiency and stent stability without additional cost or treatment delay indicate that 3D airway reconstruction could be considered for future practice. 

Source: Engineering and Technology Magazine
Author(s): Tanya Weaver

Surgeons at Baylor St Luke’s Medical Center in Houston, Texas, successfully performed the first robotic heart transplant in the U.S. without opening the chest, using small abdominal incisions. This minimally invasive procedure reduced trauma, blood loss, and infection risk, allowing for quicker recovery. The patient, who had been hospitalized since November 2024, underwent the transplant in March 2025, recovering without complications. Lead surgeon Dr. Kenneth Liao, chief of cardiothoracic transplantation and mechanical circulatory support at Baylor, emphasized the advantages of avoiding chest opening. Dr. Todd Rosengart, chair of the department of surgery at Baylor, noted that this innovative approach significantly enhances safety in complex surgery.  

Source: The Journal of Thoracic and Cardiovascular Surgery
Author(s): Haley I. Tupper, Varada Sarovar, Kian C. Banks, Julie A. Schmittdiel, Diana S. Hsu, Simon K. Ashiku, Ashish R. Patel, Lori C. Sakoda, Jeffrey B. Velotta

This study evaluated the impact of the interval between diagnosis and surgery on mortality in patients with early-stage non-small cell lunger cancer (NSCLC). The results indicated that surgeries performed more than eight weeks after diagnosis significantly increased five-year mortality and recurrence rates compared to those conducted within eight weeks. The findings suggest that minimizing the time to surgery is crucial for improving outcomes in early-stage NSCLC patients.  

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Tong Qiu, Feng Hou, Jie Wu, Zhe Wu, Wenxing Du, Jichen Yang, Yandong Zhao, Xiangfeng Jin, Zizong Wang, Kaihua Tian, Yi Shen, Haiqing Zhou, Wenjie Jiao

This study investigates the prognostic impact of tumor spread through air spaces (STAS) in early-stage synchronous multiple primary lung adenocarcinoma (sMPLA) and its interaction with surgical strategies. Among 131 patients with cT1-3N0M0 sMPLA, STAS was detected in 52 percent, including 16 percent with STAS in both tumors (bi-STAS). Bi-STAS independently predicted significantly worse overall survival and recurrence-free survival compared to mono-STAS or no STAS. Patients with bi-STAS exhibited higher mortality and recurrence rates, regardless of whether they underwent lobectomy or sublobar resection, indicating limited benefit from more extensive surgery. Prognostic factors also included tumor size, pleural invasion, and lung diffusion capacity. These findings underscore the importance of comprehensive STAS evaluation in all dominant tumors for postoperative risk stratification in sMPLA. 

Source: Annals of Surgical Oncology
Author(s): Kian C. Banks, Varada Sarovar, Angela Sun, Rachel K. Wile, Katherine E. Barnes, Jeffrey B. Velotta

This study evaluated the effect of perioperative invasive nodal staging on nodal upstaging in early-stage non-small cell lung cancer (NSCLC) patients undergoing resection. Out of 2,576 patients, only 18.7 percent underwent invasive nodal staging, with less than one percent experience unexpected N2 upstaging after surgery, and no association was found between the absence of perioperative nodal sampling and occurrence of N2 or IIIA+ disease. The findings suggest that perioperative invasive nodal staging did not significantly impact the rate of pathological N2 upstaging in early-stage NSCLC patients within the study’s health system.  

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Mateo Marin-Cuartas, Syed Zaid, Jörg Kempfert, Michael A Borger, Serdar Akansel, Thilo Noack, David Holzhey, Tsuyoshi Kaneko, Isaac George, Gorav Ailawadi, Robert L Smith , Arnar Geirrson, Ahmed El-Eshmawi, Dimosthenis Pandis, Suzanne de Waha, Nikolaos Bonaros, Fabien Praz, Maurizio Taramasso, Michele De Bonis, Lenard Conradi, Christian Hagl, Nicolas Doll, Mahmoud Wehbe, Alexey Dashkevich, Manuela de la Cuesta, Jagdip Kang, Zara Dietze, Philipp Kiefer, Gilbert H L Tang

This review article aims to examine the surgical approach to patients with failed mitral transcatheter edge-to-edge repair (M-TEER), focusing on operative challenges, decision-making, and contemporary outcome data. Technical considerations, including device removal and the management of complex mitral valve (MV) anatomy, are discussed. The authors performed a comprehensive literature review and gathered experience from high-volume centers in the surgical management of failed M-TEER. 
 
The key messages from this review are: MV surgery after failed M-TEER is a complex but increasingly necessary procedure as the use of M-TEER grows. It occurs in up to six percent of patients, with a median age of 70–76 years at the time of failure and a median time to failure of less than six months. MV surgery following M-TEER is associated with high mortality and morbidity, with a reported 30-day mortality ranging from 10–40 percent and one-year survival below 60 percent. Functional device failure, structural device failure, MV disease progression, and infective endocarditis are frequent mechanisms of M-TEER failure. Surgical MV repair is the preferred management strategy; however, due to the technical and anatomical complexity, MV replacement is performed much more frequently (with MV repair rates below 10 percent). 
 
The authors concluded that MV surgery after failed M-TEER poses technical challenges due to the presence of altered anatomy, the need for concomitant procedures, and the patient′s comorbidities. While surgical intervention carries increased risks, it remains the definitive treatment for failed M-TEER, offering durable relief from mitral regurgitation (MR). Due to the technical complexities associated with these procedures, strong consideration should be given to transferring patients requiring MV surgery after failed M-TEER to high-volume MV centers. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Prabhvir S Marway, Carlos A Campello Jorge, Rana-Armaghan Ahmad, Nicasius Tjahjadi, Himanshu J Patel, Bo Yang, Nicholas S Burris

Aortic arch tears at the time of acute type A dissection are often grouped together and are known to contribute to flow into the residual false lumen, which can increase the risk of delayed complications. This article is the first to investigate the different types of tears, namely residual arch tears (RATs) and distal anastomosis new entry tears (DANEs). It found that DANEs were associated with worse descending aorta modelling and a greater need for reintervention, while RATS were not. An interesting theory suggests that the morphology of tears may contribute to different flow dynamics. For instance, RATs may shunt blood toward the arch vessels and reduce pressure loading of the false lumen, while DANEs may not have an associated pressure relief system. This may have an important effect on technical considerations during the index dissection repair. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Lasse Visby, Simone Engdahl, Erik Lilja Secher, Hasse Møller-Sørensen, Henrik Kehlet, René Horsleben Petersen

This prospective observational study examined the association between Pain Catastrophizing Scale (PCS) scores and postoperative pain in 100 patients undergoing multiportal video-assisted thoracic surgery (VATS) lobectomy. The PCS is a 13-item self-report tool measuring catastrophic thinking related to pain, including rumination, magnification, and helplessness, with scores ranging from 0 to 52. Patients completed the PCS preoperatively, and pain was assessed twice daily for two days postoperatively during rest, coughing, use of a positive expiratory pressure (PEP) device, and a five-meter walk test. Those with high PCS scores (greater than or equal to 20) reported significantly greater pain during coughing and walking and were more likely to experience moderate-to-severe pain. Linear regression confirmed PCS as a strong predictor of increased pain. All patients received standardized ERAS protocol pain management. Incorporating PCS may enable more targeted analgesia for breakthrough pain, moving beyond opioid dose titration alone. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Hanna Dagnegård, Adriaan W Schneider, Patrick T Timmermans, Natalie Glaser, Solveig M Kolseth, Farkas Vanky, Tomas Gudbjartsson, Rune Haaverstad, Alex Cotovanu, Ulrik Sartipy, Robert J M Klautz, Morten Smerup, Jesper Hjortnaes, North Atlantic Freestyle Collaboration

There is an established difference in presentation, pattern of disease progression, and long-term outcomes in males and females presenting with cardiovascular disease. It is also known that aortic insufficiency (AI) severity and left ventricular dilatation are closely associated in males, but not in females. This article found that females who underwent aortic valve replacement with stentless bioprothesis for aortic insufficiency had worse outcomes compared to males, even after accounting for differences in age. This article raises an important question about whether risk stratification models and current guidelines for intervention in AI need to be revised due to the growing evidence of the contribution of sex to cardiovascular illness. 

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