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Journal and News Scan

Source: Artificial Organs
Author(s): Sebastian Mang, Armin Kalenka, Lars Mikael Broman, Alexander Supady, Justyna Swol, Guy Danziger, André Becker, Sabrina I. Hörsch, Thilo Mertke, Ralf Kaiser, Hendrik Bracht, Viviane Zotzmann, Frederik Seiler, Robert Bals, Fabio Silvio Taccone, Onnen Moerer, Roberto Lorusso, Jan Bělohlávek, Ralf M. Muellenbach, Philipp M. Lepper, The COVEC‐Study Group

In this article by the COVEC Study Group, they conducted a EuroELSO international survey investigating the clinical outcomes of extracorporeal membrane oxygenation (ECMO) on patients with COVID-19 Acute Respiratory Distress Syndrome (ARDS). They demonstrate that the majority of patients requiring ECMO were veno-venous rather than veno-arterial cannulation, with time on ECMO ranging between less than two weeks to more than four weeks. The majority stated that the reason for discontinuation of ECMO were lack of patient recovery at just over 50%, with the majority stating that they felt patients with COVID-19 and ARDS benefitted from ECMO therapy.

Source: The Annals of Thoracic Surgery
Author(s): Demetrios N. Mallios, MD, W. Hampton Gray, MD, Andrew L. Cheng, MD, Winfield J. Wells, MD, Vaughn A. Starnes, MD, and S. Ram Kumar, MD, PhD

This study analyzed factors associated with aortopulmonary amalgamation or Ross-Konno procedure in patients who underwent surgical repair for interrupted aortic arch/VSD.

Source: The Annals of Thoracic Surgery
Author(s): Yusuf S. Abdullahi, PhD,* Mohammad Yousuf Salmasi, MBBS,* Marco Moscarelli, MD, Alessandra Parlanti, MSc, Marco Marotta, MD, Egidio Varone, MD, Marco Solinas, MD, Rahuman M. Sheriff, PhD, Roberto P. Casula, FRCS, and Thanos Athanasiou, PhD, FRCS

This study evaluates the importance of of evaluating patient frailty prior to high-risk cardiothoracic operations.

Source: The Annals of Thoracic Surgery
Author(s): Andrew Tang, MD, MS, Hafiz U. Siddiqui, MD, Lucy Thuita, MS, Jesse Rappaport, MD, Alejandro C. Bribriesco, MD, Kenneth R. McCurry, MD, James Yun, MD, Shinya Unai, MD, Marie Budev, DO, MPH, Sudish C. Murthy, MD, PhD, Eugene H. Blackstone, MD, and Usman Ahmad, MD

This study analyzed 1039 adult patients from 2006 to 2017 to determine the rate of pleural complications after lung transplantation.

Source: JAMA Cardiology
Author(s): Prahlad Karki, MD; Surendra Uranw, MPH; Santosh Bastola, MSc; et al.

Rheumatic heart disease (RHD) continues to be responsible for major cardiovascular morbidity and mortality in the developing world.  It constitutes a double tragedy because it disproportionately affects economically disadvantaged people and young people, thereby robbing them of the most productive years of life. Often, by the time it is diagnosed, RHD has resulted in substantial valvular damage.  This cluster randomized clinical trial investigates if school-based echocardiographic screening in combination with secondary antibiotic prophylaxis in children with evidence of latent rheumatic heart disease may be an effective strategy to reduce the prevalence of definite or borderline rheumatic heart disease in endemic regions.

Source: The New England Journal of Medicine (NEJM)
Author(s): Jason G. Andrade, George A. Wells, Marc W. Deyell, Matthew Bennett, Vidal Essebag, Jean Champagne, Jean-Francois Roux, Derek Yung, Allan Skanes, Yaariv Khaykin, Carlos Morillo, Umjeet Jolly, Paul Novak, Evan Lockwood, Guy Amit, Paul Angaran, John Sapp, Stephan Wardell, Sandra Lauck, Laurent Macle, Atul Verma. for the EARLY-AF Investigators

A Canadian multi-centre RCT of immediate baloon-cryoablation of the pulmonary veins: the intervention was compared to the relevant standard of pharmacological care. The target population was treatment-naive sufferers of de novo paroxysmal atrial fibrillation. The recruitment was successful, and unrestricted funding was secured from the healthcare device industry. The freedom from asymptomatic and symptomatic paroxysms of atrial fibrillation appeared improved at one-year follow-up.
It would be very interesting to additionally see the cardiovascular outcomes of the cohort, the thromboembolic events in particular, given that the subjects remained free from the atrial fibrillation for 99% of that year (having been continuously monitored).
The trial holds some interest for the cardiovascular surgeons practising ablation: The publication comes in the wake of a manuscript suggesting there is an underutilization of ablation during mitral surgery. (

Source: The Annals of Thoracic Surgery
Author(s): J. Hunter Mehaffey, MD, MSc, Elizabeth Krebs, MD, MSc, Robert B. Hawkins, MD, MSc, Eric J. Charles, MD, PhD, Shawn Tsutsui, BS, Irving L. Kron, MD, Alan M. Speir, MD, Mohammed Quader, MD, Leora Yarboro, MD, Kenan Yount, MD, MBA, and Gorav Ailawadi, MD

This study looked into the implementation of concomitant surgical ablation for atrial fibrillation during mitral valve surgery.

Source: Journal of Thoracic Oncology
Author(s): Jean-Louis Pujol, Pascal-Alexandre Thomas, Philippe Giraud, Marc G. Denis, Brigitte Tretarre, Benoît Roch, Sebastien Bommart

An open-access detailed editorial from the official periodical of the International Association for the Study of Lung Cancer

Source: The Annals of Thoracic Surgery
Author(s): Zara Khachatryan, Josephina Haunschild, Konstantin von Aspern, Michael A. Borger, Christian D. Etz

This is a comprehensive review on ischemic spinal cord injury following of descending and thoracoabdominal aortic repair, including monitoring, early diagnosis, blood and cerebrospinal fluid biomarkers, and preventive measures. 

Source: European Journal of Vascular & Endovascular Surgery
Author(s): Stavros K. Kakkos , Manjit Gohel , Niels Baekgaard , Rupert Bauersachs, Sergi Bellmunt-Montoya , Stephen A. Black , Arina J. ten Cate-Hoek , Ismail Elalamy , Florian K. Enzmann , George Geroulakos , Anders Gottsäter, Beverley J. Hunt, Armando Mansilha , Andrew N. Nicolaides , Per Morten Sandset , Gerard Stansby , ESVS Guidelines Committee , Gert J. de Borst, Frederico Bastos Gonçalves, Nabil Chakfé, Robert Hinchliffe, Philippe Kolh, Igor Koncar, Jes S. Lindholt, Riikka Tulamo, Christopher P. Twine, Frank Vermassen, Anders Wanhainen, Marianne G. De Maeseneer, Anthony J. Comerota, Peter Gloviczki, Marieke J.H.A. Kruip, Manuel Monreal, Paolo Prandoni, Melina Vega de Ceniga

A recent European consensus paper. Relatively easily read, and favouring meta-analyses over randomised trials. The bulk of the manuscript is of interest to all healthcare providers. The chapters 2.8.1 and 3.1.2 are of additional relevance to the ctsnet readership, as they summarise guidance on interventions. The chapter is also of value with regards to reversal of novel oral anticoagulants.