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Journal and News Scan

Source: MedPage Today
Author(s): Kristin Jenkins

Using eight computed tomography radiographic features in an automated algorithm, differentiating between benign and malignant status of indeterminate pulmonary nodules had an area under the curve of 0.939. 

Source: JAMA
Author(s): Xiaoxi Yao, Bernard J. Gersh, David R. Holmes Jr, Rowlens M. Melduni, Daniel O. Johnsrud, Lindsey R. Sangaralingham, Nilay D. Shah, Peter A. Noseworthy

This review of over 75,000 patients from a large administrative database found that occlusion of the left atrial appendage during cardiac surgery was associated with a reduced risk of subsequent stroke and all-cause mortality.

Source: Nature Biomedical Engineering
Author(s): M. Saad Bhamla, Brandon Benson, Chew Chai, Georgios Katsikis, Aanchal Johri, Manu Prakash

A centrifuge made of paper and string and powered by hand can separate plasma from whole blood in 90 seconds and permit the diagnosis of malaria in 15 minuntes at the point of care. The centrifuge generates speeds of 125,000 rpm, with a theoretical maximum of 1,000,000 rpm. Such devices may become the centerpiece of diagnostic assays in the developing world in the future.

Source: Nature Reviews Cardiology
Author(s): David A. Brown, Justin B. Perry, Mitchell E. Allen, Hani N. Sabbah, Brian L. Stauffer, Saame Raza Shaikh, John G. F. Cleland, Wilson S. Colucci, Javed Butler, Adriaan A. Voors, Stefan D. Anker, Bertram Pitt, Burkert Pieske, Gerasimos Filippatos, Stephen J. Greene, Mihai Gheorghiade

An interesting, informative, and timely consensus statement on mitochondrial dysfunction in heart failure and how to potentially target these abnormalities therapeutically.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Yves d’Udekem, James S Tweddell, Tom R Karl

d’Udekem and colleagues discuss aortic valve surgery in infants and neonates. The authors highlight issues such as considerations and strategies, the role of associated intracardiac and extracardiac lesions, how to deal with iatrogenic lesions following interventional catheter or surgical procedures, and techniques and limitations of aortic valve repair.

Source: JAMA
Author(s): Emmanuel Martinod, Kader Chouahnia, Dana M. Radu, Pascal Joudiou, Yurdagul Uzunhan, Morad Bensidhoum, Ana M. Santos Portela, Patrice Guiraudet,Marine Peretti, Marie-Dominique Destable, Audrey Solis, Sabiha Benachi, Anne Fialaire-Legendre, Hélène Rouard, Thierry Collon, Jacques Piquet, Sylvie Leroy, Nicolas Vénissac, Joseph Santini, Christophe Tresallet, Hervé Dutau, Georges Sebbane, Yves Cohen, Sadek Beloucif, Alexandre C. d’Audiffret, Hervé Petite, Dominique Valeyre, Alain Carpentier, Eric Vicaut

A landmark article summarizing the early clinical experience of using a cryopreserved aortic homograft with a customized internal stent for major airway replacement.

Source: The Annals of Thoracic Surgery
Author(s): Linda W. Martin, Bethany M. Sarosiek, Meredith A. Harrison, Traci Hedrick, James M. Isbell, Alexander S. Krupnick, Christine L. Lau, J. Hunter Mehaffey, Robert H. Thiele, Dustin M. Walters, Randal S. Blank

Enhanced recovery programs are very popular now, but their benefits have been mostly theoretical.  This article describes challenges and outcomes after initiation of such a program, citing decreased costs, lower opioid usage, and shortened length of stay.

Source: MedPage Today
Author(s): Shalmali Pal

This overview of some recent social science flavored research identifies challenges associated with stigma attached to a lung cancer diagnosis.  These challenges include decreased participation in screening tests, noncompliance with therapy, and poor communication with treating physicians.

Source: ESTS
Author(s): European Society of Thoracic Surgeons

The Thoracic community is ready to gather in Ljubljana this year for the biggest event of purely thoracic surgery interest. The full programme is availabe on the website. Looking forward to learning the latest advancements in General Thoracic Surgery directly from experts from all around the globe!

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Umberto Benedetto, Stuart J Head, Gianni D Angelini, Eugene H Blackstone

Propensity scores methods have proven incredibly useful in the analysis of observational datasets, as they allow for control of confounding variables. Moreover, they offer several benefits over the more ubiquitous multivariable regression approaches. Propensity score matching is a familiar tool, however there are several other propensity score-based methods, such as weighting and stratification. Benedetto and colleagues explore these different approaches and illustrate the methodology using a real-world example.