ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Journal and News Scan

Source: New England Journal of Medicine
Author(s): Wolfe GI, Kaminski HJ, Aban IB, Minisman G, Kuo HC, Marx A, Ströbel P, Mazia C, Oger J, Cea JG, Heckmann JM, Evoli A, Nix W, Ciafaloni E, Antonini G, Witoonpanich R, King JO, Beydoun SR, Chalk CH, Barboi AC, Amato AA, Shaibani AI, Katirji B, Lecky BR, Buckley C, Vincent A, Dias-Tosta E, Yoshikawa H, Waddington-Cruz M, Pulley MT, Rivner MH, Kostera-Pruszczyk A, Pascuzzi RM, Jackson CE, Garcia Ramos GS, Verschuuren JJ, Massey JM, Kissel JT, Werneck LC, Benatar M, Barohn RJ, Tandan R, Mozaffar T, Conwit R, Odenkirchen J, Sonett JR, Jaretzki A 3rd, Newsom-Davis J, Cutter GR; MGTX Study Group.
A small international prospective randomized trial of extended thymectomy with steroids vs steroids for 126 with class II to IV myasthenia gravis.  The selection criteria and powering were altered mid-trial. Surgery was associated with a better symptom score, lower dose of predisone, less use of immunosuppresives, and fewer hospitalizations at 3 years.  The positive outcomes are of surgical relevance as they may lead to a considerable increase of referrals for OPEN thymectomies! I assume that longer term outcomes will be forthcoming.
Source: Journal of the American Medical Association
Author(s): Stephan Haussig; Norman Mangner; Michael G. Dwyer; Lukas Lehmkuhl; Christian Lücke; Felix Woitek; David M. Holzhey; Friedrich W Mohr; Matthias Gutberlet; Robert Zivadinov; Gerhard Schuler; Axel Linke
In this study the investigators aimed to study whether a cerebral protection device during TAVI reduced the number of cerebral lesions in patients undergoing TAVI. In total, 100 patients undergoing TAVI between April 2013 and June 2014 were randomized to either the filter or control group. The number of new lesions at 2 days after TAVI, as measured by diffusion-weighted magnetic resonance imaging (DWMRI), was lower in the filger group (4.00 versus 10.00 in the control group, p<0.001). Also lesion volume was lower in the filter group. Adverse events were similar in the filter and control group. This small randomized study shows that a cerebral protection device reduced the frequency of ischemic cerebral lesions after TAVI. Further larger studies are needed to assess the beneficial effect on neurological and cognitive functioning. 
Source: Perfusion. 2016 Jul 21
Author(s): Guajardo Salinas GE, Nutt R, Rodriguez-Araujo G.
This is a retrospective study comparing outcomes of conventional 1:4 cardioplegia vs 4:1 Del Nido cardioplegia on adult patients undergoing CABG. 249 consecutive patients underwent coronary artery bypass using blood cardioplegia and 159 using del Nido Cardioplegia. Authors found no significances in CPB time, X-clamp time, in-hospital mortality or length of stay between these two groups.  However, they found that patients with Del Nido had less defibrillation need, less blood transfusion rate and transfusion volume, as well as less Hgb change. Most patients had spontaneous return of sinus rhythm.
Source: Journal of Thoracic and Cardiovascular Surgery
Author(s): Kannan RY
A bona fide new technique applied in a handful of low-risk deep sternal wound infections. It will be interesting to see the follow-up and perhaps some cardiothoracic surgical input to the efforts of the esteemed plastic surgical colleague who is the sole author.
Source: Journal of Cardiac Surgery
Author(s): Márcio Madeira, Catarina Martins, Giovanna Koukoulis, Marta Marques, João Reis and Miguel Abecassis
The authors reviewed the role of mechanical thrombectomy in patients who develop strokes following cardiac surgery in their own center and from the literature. They conclude that mechanical thrombectomy is indicated for those patients who develop a stroke following cardiac surgery in whom systemic thrombolysis  is contraindicated and when the thrombectomy can be performed within 6 hours of the onset of the stroke
Source: Journal of Cardiac Surgery
Author(s): Salah E. Altarabsheh, Salil V. Deo, Shannon M. Dunlay, Yaqthan M. Obeidat, Patricia J. Erwin, Abeer Rababa'h, Nagaraju Sarabhu, Suparna Navale, Yang Hyun Cho, Harveen K. Lamba, Alan H. Markowitz and Soon J. Park
This was a meta-analysis of 15 retrospective studies involving 7123 valve prostheses performed in patients with end-stage renal disease (ESRD). The results showed that bleeding complications were significantly higher with mechanical valves and that structural degeneration of tissue valves during the follow-up period was low.  The authors concluded that in patients with ESRD, tissue valves  should be the prosthesis of choice.
Source: Journal of Cardiac Surgery
Author(s): Philippe Primo Caimmi, Maurizio Sabbatini, Luca Fusaro, Alessia Borrone and Mario Cannas
This study investigated the mechanical properties of ePTFE sutures used for artificial chordae during mitral valve repair. The study revealed that chordae greater than 3cm in length are associated with increased stiffness.  This suggests that repairs, using minimally invasive OFF PUMP beating heart techniques, which anchor ePTFE neochordae to the ventricular apex, may have less durability than when anchored to the tips of the papillary muscles.
Source: Journal of Thoracic Oncology
Author(s): Bing-Yen Wang, Jing-Yang Huang, Ching-Hsiung Lin, Jiunn-Liang Ko, Chen-Te Chou, Yu-Chung Wu, Sheng-Hao Lin, Yung-Po Liaw
Using a Taiwanese national database, the authors evaluated long-term survival after VATS vs open lobectomy for lung cancer using propensity matching and multvariate analyses.  Among 5,222 patients, 2,164 (41%) had a VATS approach.  Propensity matching yielded 1848 patients in each group.  5-year survival was similar for the VATS and open groups (68.7% vs 65.5%).  Surgical resection was not an independent predictor of survival.
Source: Interact CardioVasc Thorac Surg
Author(s): Giuseppe Gatti, Luca Dell'Angela, Marco Morosin, Luca Maschietto, Bruno Pinamonti, Bernardo Benussi, Gabriella Forti, Gian Luigi Nicolosi, Gianfranco Sinagra, and Aniello Pappalardo
The authors compared the results of annuloplasty with flexible and rigid rings in patients with tricuspid valve regurgitation. This is a propensity score-matched analysis with 98 pairs. They concluded that both rings are equally effective, however the rigid one causes a more complete right heart reverse remodelling. 
Source: Eur J Cardiothorac Surg
Author(s): Annabel J. Sharkey, Rocco Bilancia, Sara Tenconi, Apostolos Nakas, and David A. Waller
The authors describe their experience with radical resection by either extrapleural pneumonectomy or extended pleurectomy–decortication (EPD) for management of pleural mesothelioma. They present pathologic findings, progression and outcome and discuss the results with caution.

Pages