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Journal and News Scan

Source: tctMD
Author(s): Michael O'Riordan

Several surgical associations have given a new statement in response to the new Valve Academic Research Consortium (VARC) definitions for aortic valve clinical studies. They took issue with a few things, most notably, rehospitalization, bleeding, and myocardial infarction.

Source: Medical News Today
Author(s): Katharine Lang

Doctors at Duke University Hospital have successfully transplanted a heart combined with a processed allogeneic thymus tissue. The recipient was a baby who of six months and has now just celebrated his first birthday. The infant now seems to be producing the immune cells needed to reduce or even eliminate the need for long-term treatment with antirejection drugs.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Patrick O Myers, MD, Victor Dayan, MD, Wilson Y Szeto, MD, Vinod H Thourani, MD, S Chris Malaisrie, MD, Marc R Moon, MD, Richard L Prager, MD, Minoru Ono, MD, Yutaka Okita, MD, Nicholas Freemantle, PhD, Milan Milojevic, MD, PhD

This is a joint position statement from EACTS, LACES, ASCVTS, AATS, and STS regarding the VARC-3 Definitions for Aortic Valve Clinical Research.

Source: The Annals of Thoracic Surgery
Author(s): Niv Ad, MD Paul S. Massimiano, MD Anthony J. Rongione, MD Bradley Taylor, MD, MPH Stefano Schena, MD Diane Alejo, BA Clifford E. Fonner, BA Rawn Salenger, MD Glenn Whitman, MD Thomas S. Metkus, MD Sari D. Holmes, PhD

The link between blood transfusion and adverse outcome is well noted in cardiac surgery. However, the rising significance of each unit transfused, whether red blood cell (RBC) or non-RBC, is not fully known. This study looked at the relationship of patient outcomes with the type and number of blood product units transfused.

Source: The Annals of Thoracic Surgery
Author(s): Shruti M. Raja, MD, MHS Jeffrey T. Guptill, MD, MHS Alec McConnell, MS Hussein R. Al-Khalidi, PhD Matthew G. Hartwig, MD Jacob A. Klapper, MD

There is clinical equipoise surrounding the perioperative and long-term effects of autoimmune myasthenia gravis (MG) patients undergoing open versus minimally invasive thymectomy, particularly for nonthymomatous MG. This analysis utilizes multicenter, real-world clinical evidence to assess perioperative complications of open and minimally invasive thymectomy techniques in MG patients.

Source: The Annals of Thoracic Surgery
Author(s): Tom C. Nguyen, MD Vinod H. Thourani, MD Alexander P. Nissen, MD Robert H. Habib, PhD Joseph A. Dearani, MD Allan Ropski, MS Juan A. Crestanello, MD David M. Shahian, MD Jeffrey P. Jacobs, MD Vinay Badhwar, MD

COVID-19 has changed many aspects of the world, and the United States continues to gather the largest number of COVID-related deaths. There is a paucity of data surrounding the effect of COVID-19 on adult cardiac surgery trends and outcomes on regional and national levels.

Source: World Journal for Pediatric and Congenital Heart Surgery
Author(s): Bahaaldin Alsoufi, Jessica H. Knight, James St. Louis, Geetha Raghuveer, Lazaros Kochilas

The Pediatric Cardiac Care Consortium was queried for patients undergoing repair of conotruncal abnormalities and subsequent AVR 1982 - 2003.   Of 106 patients undergoing AVR, the operative mortality was 12%, and was related to infant age at the time of surgery (OR = 55).   Transplant-free survival at 25 years was 53%.  Transplant-free survival at 20 years was inferior to that of patients undergoing AVR for non-conotruncal abnormalities (61% vs 82%).  Valve type was not associated with outcomes.

Source: Circulation Research
Author(s): Tiffany M. Powell-Wiley, Yvonne Baumer, Foster Osei Baah, Andrew S. Baez, Nicole Farmer, Christa T. Mahlobo, Mario A. Pita, Kameswari A. Potharaju, Kosuke Tamura and Gwenyth R. Wallen

A paper that addresses a gap in knowledge and will guide future research: of particular interest, the penultimate paragraph on The Role of Interventions.

Source: The Annals of Thoracic Surgery
Author(s): Sara K. Pasquali, MD, MHS Dylan Thibault, MS Matt Hall, PhD Karen Chiswell, PhD Jennifer C. Romano, MD J. William Gaynor, MD David M. Shahian, MD Marshall L. Jacobs, MD Michael G. Gaies, MD, MPH Sean M. O’Brien, PhD Edward C. Norton, PhD Kevin D. Hill, MD, MS Patricia A. Cowper, PhD Samir S. Shah, MD, MSCE John E. Mayer, MD Jeffrey P. Jacobs, MD

More than 40,000 children in the United States are undergoing congenital heart surgery annually. Yet, the relationship between hospital quality and costs remains unclear. This article explores this issue.

Source: Circulation Research
Author(s): Olujimi A. Ajijola

An interesting brief editorial on an experiment revisiting renal denervation as a panacea to cardiovascular disease