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Journal and News Scan

Source: Annals of Thoracic Surgery
Author(s): Nishant D. Patel, Diane Alejo, Todd Crawford, Narutoshi Hibino, Harry C. Dietz, Duke E. Cameron, Luca A. Vricella
Surgery for treatment of this aortopathy entailing aortic root replacement was assessed in this single institution retrospective study of 34 children.  90% had valve sparing surgery; there was no operative mortality.  Reintervention is commonly needed, and frequent surveillance imaging is recommended.
Source: Annals of Thoracic Surgery
Author(s): Daniel P. O’Hair, Tanvir K. Bajwa, Stanley J. Chetcuti, G. Michael Deeb, Robert C. Stoler, Robert F. Hebeler, Brijeshwar Maini, Mubashir Mumtaz, Neal S. Kleiman, Michael J. Reardon, Shuzhen Li, David H. Adams, Daniel R. Watson, Steven J. Yakubov, Jeffrey J. Popma, George Petrossian
Using data from the CoreValve US Expanding Use Study, outcomes for patients with end stage renal disease (ESRD) undergoing TAVR were evaluated using an endpoint of all-cause mortality or major stoke at 1 year.  Mortality at 1 year was 30%, and the stroke incidence was 2.1%.  New permanent pacemaker need was 27%.  The 1-year mortality appears increased compared to patients without ESRD.  
Source: Annals of Thoracic Surgery
Author(s): Todd C. Crawford, J. Trent Magruder, Joshua C. Grimm, Clinton D. Kemp, Alejandro Suarez-Pierre, Kenton J. Zehr, Kaushik Mandal, Glenn J. Whitman, John V. Conte, Robert S. Higgins, Duke E. Cameron, Christopher M. Sciortino
UNOS data for over 14,500 isolated heart transplant patients were analyzed to assess the relationship between donor distance from the transplantation center and recipient mortality at 30 days and 1 year.   Ischemic time correlated with donor distance.  Mortality was reduced for donor distances over 25 miles, and the reduction was highest for distances greater than 500 miles.  
Source: European Heart Journal
Author(s): Antonio H. Frangieh, Albert Markus Kasel
Bicuspid aortic valve (BAV) has been considered a relative contraindication for transcatheter aortic valve implantation (TAVI). Nevertheless, favourable results have been reported from registries and observational reports. In this manuscript, the authors present some useful technical considerations and tips-and-tricks for use during TAVI procedures in BAV.
Source: Circulation Research
Author(s): David D. Waters, Priscilla Y. Hsue
A short and readable commentary on monoclonal antibodies and dyslipidaemias, particularly on FOURIER,  SPIRE and ODYSSEY trials
Source: New England Journal of Medicine
Author(s): D.S. Jones
With the 50th birthday of CABG, the New England Journal of Medicine published this nice article on the history and development of CABG.
Source: The Guardian
Author(s): Mukesh Kapila
I was moved by this editorial on global health matters in a daily British newspaper by an  academic medical  colleague,  written in response to anticipated changes in the leadership of the  World Health Organisation. It is perhaps time for us surgeons to augment our administrative participation in global healthcare. 
Source: Nature
Author(s): the TRACERx Consortium
Researchers conducted a  study, published in Nature, to investigate whether this genetic diversity could be tracked clinically. Using blood samples from 96 of the 100 patients, they demonstrated that the patchwork of genetic faults present in non-small cell lung cancer, could be monitored using bits of DNA in the blood that have broken off from a tumour (circulating tumour DNA). They then analysed blood taken from 24 patients after surgery, and accurately identified more than 90 per cent of those destined to relapse – up to a year before clinical imaging could confirm the disease’s return. This finding opens up numerous opportunities for new drug trials to try to prevent lung cancer relapse. Monitoring benefit from chemotherapy after surgery is not currently possible as there are often no clinical signs of disease.   see original article here https://www.nature.com/nature/journal/vaap/ncurrent/full/nature22364.html  
Source: New York Post
Author(s): Brian Costello
He went to Stanford University and got the surgery. Shortly after, Coleman said he wanted to play football again. “Right after surgery, I put two and two together,” Coleman said. “If I’m fixed, I can play football again, right?” He talked to his surgeon and cardiologist, who both gave him their blessing. Then he talked to the coach at his high school, who welcomed him. Just a few months after surgery, Coleman was on the football field. He played the final two regular-season games and four playoff games. He returned an interception 26 yards for a touchdown in his first game.
Source: Medpagetoday
Author(s): by Kristina Fiore , Deputy Managing Editor, MedPage Today
Two European physicians attempting to attend the American Association for Thoracic Surgery meeting in Boston last weekend -- the organization's Centennial -- were turned away by U.S. Customs agents because of their recent travel to certain Middle Eastern countries. Rock-star thoracic surgeon Pieter Kappetein, MD, PhD, of Erasmus Medical Center in Rotterdam in the Netherlands, and Bernard Eisenmann, MD, former chief of cardiovascular surgery at University Hospital Strasbourg in France, were stopped at U.S. Customs in Dublin and Montreal, respectively, and had to book new flights back to Europe.

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