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Journal and News Scan

Source: The Lancet Respiratory Medicine
Author(s): The PROTHOR Collaborative Group of the PROtective VEntilation Network (PROVE Network) for the Clinical Trial Network of the European Society of Anaesthesiology and Intensive Care

In this international randomized trial involving 2,124 thoracic surgery patients requiring one-lung ventilation, the authors compared high positive end-expiratory pressure (PEEP) with recruitment maneuvers (10 cm H2O) to standard low PEEP without recruitment (5 cm H2O). Despite improved oxygenation and lower driving pressures with the high-PEEP strategy, there was no significant reduction in postoperative pulmonary complications (53.6 percent vs 56.4 percent). High PEEP caused substantially more intraoperative hypotension and arrhythmias, whereas hypoxemia occurred more often with low PEEP. Postoperative outcomes, including mortality and extrapulmonary complications, were similar between the groups. These findings indicate that routine intraoperative lung-expansion strategies do not improve pulmonary outcomes in this setting, and PEEP selection should instead be individualized based on real-time gas-exchange and hemodynamic status. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Ujjawal Kumar, Aravinda Page, Sambhavi Kumar, Daniel Sitaranjan, Harry Smith, Fadi Al-Zubaidi, Ravi De Silva, Shakil Farid

This 10-year, single institution propensity-matched study investigated the outcomes of supervised resident-led emergency cardiac surgery compared to consultant-led procedures. Among 1,241 emergency cases, 364 matched pairs were analyzed, and overall outcomes were noted to be similar. Despite longer cardiopulmonary bypass times in consultant-led cases—possibly suggesting greater complexity—there were no significant differences in in-hospital mortality (13.7 percent vs 13.5 percent), major complications, or long-term survival up to 10 years. Subgroup analyses focusing on high-risk cases, emergent revascularization, infective endocarditis, and acute aortic syndromes confirmed comparable outcomes. The authors suggest that these findings validate structured training programs that progressively increase resident autonomy under supervision, addressing concerns about reduced training duration and working-hour restrictions. The study supports the safety and efficacy of resident involvement in high-stakes emergency cardiac surgery, demonstrating that appropriate supervision enables skill development without compromising patient outcomes. 

Source: Langenbeck's Archives of Surgery
Author(s): Vincent Q. Sier, Merel J. Verhagen, Maurits Zegel, Roderick F. Schmitz, Carla S.P. van Rijswijk, Jan van Schaik, Eduard J.E.T. Schmidt, Jaap F. Hamming, Abbey Schepers, Inez J. Wijdh-den Hamer, Mark C. Burgmans, Jesper Hjortnaes, Joost R. van der Vorst

This cross-sectional study compared the personality traits of 224 Dutch vascular surgeons, cardiothoracic surgeons, and interventional radiologists using the validated Big Five Inventory-2. While all specialists showed higher levels of open-mindedness, conscientiousness, extraversion, and agreeableness, along with lower levels of negative emotionality compared to the general population, notable differences emerged between the specialties. Cardiothoracic surgeons were found to be more agreeable than interventional radiologists, while vascular surgeons showed lower levels of negative emotionality. Facet-level analyses revealed distinctions in compassion, creative imagination, and assertiveness. These differences suggest that unique personality patterns exist even among professionals working within similar cardiovascular care pathways. Importantly, personality differences have been linked with surgical outcomes, clinical decision-making, and teamwork, and should be investigated further. 

Source: Methodist Debakey Cardiovascular Journal
Author(s): Jacob Watson, Alan Lumsden, Charudatta Bavare

In this article, the authors review the current and emerging role of robotic-assisted surgery in vascular surgery. They describe the evolution of surgical robotic systems and summarize evidence on robotic procedures such as aortoiliac reconstruction, internal thoracic artery (ITA) harvesting, heart transplantation, renal vein transposition, and inferior vena cava interventions. While early results demonstrate technical feasibility, improved precision, and reduced recovery times, limitations persist, including high costs, lack of vascular-specific instruments, and the absence of formal training programs. The authors emphasize the need for dedicated curricula, specialized tools, and collaborative innovation to advance robotic vascular surgery. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Ming Hao Guo, Jehangir J Appoo, Philippe Demers, Hafsa ES, Arminder Jassar, Himanshu J Patel, William Brinkman, Maral Ouzounian, Rony Atoui, Juan B Grau, John Bozinovski, Michael W A Chu, Nimesh Desai, Francois Dagenais, G Chad Hughes, IV, Kevin Lachapelle, Zlatko Pozeg, Elaine E Tseng, Puja Kachroo, Richard Whitlock, Ismail El-Hamamsy, Cristian R Baeza, Anthony L Estrera, Eric Herget, George A Wells, Munir Boodhwani

This multicenter study from the TITAN trial examined the quality of life in 157 patients with moderate ascending thoracic aortic aneurysms (ATAA) undergoing surgery (n=52) or surveillance (n=105) between 2019 and 2022. After propensity matching and a 13-month follow-up using short form survey (SF)-36 questionnaires, surgical patients who underwent surgery showed significantly greater improvements compared to those receiving surveillance in mental component summary scores, general health, and mental health. The study concluded that surgical treatment of moderate ATAAs improves the mental aspects of quality of life at one year compared to surveillance. 

Source: Circulation
Author(s): Alexis K. Okoh, Lambert T. Appiah, Yaw A. Wiafe, Michael K. Amponsah, Setri S. Fugar, Ebru Ozturk, Yaw Adu-Boakye, Isaac Kofi Owusu, Bernard Cudjoe Nkum, Bert-Jan van den Born, Charles Agyemang, Amit J. Shah, Modele O. Ogunniyi

This study explores the use of artificial intelligence (AI) for auscultation in diagnosing heart failure in Sub-Saharan Africa, highlighting its potential to improve access to cardiovascular care in resource-limited settings. The research demonstrates that AI-based auscultation tools can effectively identify heart failure, offering a solution for early detection and management in regions with limited specialist availability. This approach may help bridge gaps in cardiovascular health equity by supporting timely diagnosis and intervention.  

Source: The New England Journal of Medicine
Author(s): Martin B. Leon, Michael J. Mack, Philippe Pibarot, Rebecca T. Hahn, Vinod H. Thourani, S.H. Kodali, Philippe Généreux, Samir R. Kapadia, David J. Cohen, Stuart J. Pocock, Yiran Zhang, Molly Szerlip, Julien Ternacle, S. Chris Malaisrie, Howard C. Herrmann, Wilson Y. Szeto, Mark J. Russo, Vasilis Babaliaros, Tamim Nazif, John G. Webb, Raj R. Makkar

The authors report seven-year outcomes of the PARTNER 3 trial comparing transfemoral transcatheter aortic valve replacement (TAVR) with surgical aortic valve replacement (SAVR) in 1,000 low-risk patients with severe, symptomatic aortic stenosis. At seven years, there were no significant differences between groups in the primary composite endpoints of death, stroke, or rehospitalization (34.6 percent for TAVR vs 37.2 percent for SAVR; HR 0.87, 95 percent CI 0.70–1.08). Mortality was similar (19.5 percent vs 16.8 percent), as were stroke (8.5 percent vs 8.1 percent), and valve failure (6.9 percent vs 7.3 percent). Valve hemodynamics and patient-reported outcomes remained stable. TAVR resulted in less atrial fibrillation but had higher rates of pacemaker implantation and paravalvular regurgitation. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Brian Swinnen, Jules R Olsthoorn, Casper Mihl, Martijn W Smulders, Sandeep K Singh, Thomas van Brakel, Iwan C C van der Horst, Alma M A Mingels, Patrick O Myers, Arnoud W J van 'tHof, Anton P M Gorgels, Matthias Thielmann, Raffaele De Caterina, Rui J Cerqueira, Nikolaos Bonaros, Wouter Oosterlinck, Steven Jacobs, Roberto Lorusso, Elham Bidar, Joachim E Wildberger, Jos G Maessen, Mario Gaudino, Can Gollmann-Tepeköylü, Samuel Heuts

This international EACTS-endorsed survey assessed current practices and sought consensus on defining periprocedural myocardial infarction (PMI) after coronary artery bypass grafting (CABG). Among 175 respondents from 29 countries, 46.4 percent reported using a specific PMI definition, with the most common being the Universal Definition of Myocardial Infarction (UDMI-4). Proposed biomarker thresholds for PMI varied, depending on the presence of supporting imaging evidence. Respondents emphasized diagnostic sensitivity over specificity (79.8 percent vs 20.2 percent). The study reveals substantial heterogeneity in clinical practice and underscores the need for a standardized CABG-specific PMI definition with high diagnostic accuracy to ensure consistent reporting and clinical interpretation. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Ahmet Bilgili, Jordyn Pendarvis, Omar M Sharaf, Giles J Peek, Mark Steven Bleiweis, Jeffrey Phillip Jacobs

This study analyzed 3,394 pediatric congenital heart disease (CHD) patients listed for heart transplant from 2014 to 2023. Of these, 16.5 percent received ventricular assist device (VAD) support while waitlisted. Waitlist mortality was higher in the VAD group (25.7 percent vs 16.2 percent). Among 2,248 transplanted patients, VAD-supported cases showed similar post-transplant events and five-year survival compared to non-VAD patients. VAD use increased from 20 to 73 cases annually. It was concluded that pediatric CHD patients bridged-to-transplant with VAD achieve comparable long-term survival to those without VAD. 

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Evgenij V Potapov, Glenn Whitman, Ranjit John, Pia Lanmüller, Zuzana Tucanova, Rakesh C Arora, Pavan Atluri, Eric E C de Waal, Gloria Faerber, Antonio Loforte, Roberto Lorusso, David L S Morales, Ivan Netuka, Francis D Pagani, Can Gollmann-Tepeköylü, Andrew Shaffer, Scott C Silvestry, Louis H Stein, Hiroo Takayama, Steven S L Tsui, Leora T Yarboro, Daniel Zimpfer, Milan Milojevic, EACTS/STS/AATS Scientific Document Group

The European Association for Cardio-Thoracic Surgery (EACTS), The Society of Thoracic Surgeons (STS), and The American Association for Thoracic Surgery (AATS) recently released joint consensus guidelines on use of temporary mechanical circulatory support (tMCS). This field has evolved significantly during the past decade. This document comprehensively discusses the goals of tMCS, device selection and various configurations, patient evaluation and selection, as well as contraindications to the use of such devices. These comprehensive guidelines also discuss their role in heart failure, including their use as a bridging strategy, monitoring and anesthetic management in patients with tMCS, postoperative management in the ICU—including ventilator strategies, renal management, anticoagulation techniques—as well as ultimate weaning and explantation techniques. 

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