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Journal and News Scan

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Erik Beckmann, Andreas Martens, Heike Krüger, Wilhelm Korte, Tim Kaufeld, Alissa Stettinger, Axel Haverich, Malakh Lal Shrestha

This is a retrospective cohort analysis of more than 500 patients undergoing the David I procedure. They specifically looked into the outcome of 50 patients with bicuspid aortic valve undergoing this procedure. While the freedom from reoperation was not different between the two groups, the freedom from reoperation at 10 years was 79% in bicuspid valve patients. Unfortunately, the authors cannot provide markers of success for the David I procedure in patients with bicuspid valves, like geometric findings of the valve prior to reconstruction. However, these results are very encouraging for valve repair success in patients with bicuspid aortic valves.

Source: The Annals of Thoracic Surgery
Author(s): Julia Dumfarth, Markus Kofler, Lukas Stastny, Simone Gasser, Michaela Plaikner, Severin Semsroth, Christoph Krapf, Thomas Schachner, Nikolaos Bonaros, Michael Grimm

This study assessed the association between preoperative neurologic dysfunction and postoperative neurologic injury in the diagnosis of acute type A aortic dissection.

Source: European Journal of Cardio-Thoracic Surgery
Author(s): Amedeo Anselmi, Vincent Galand, André Vincentelli, Stéphane Boule, Camille Dambrin, Clément Delmas, Laurent Barandon, Mathieu Pernot, Michel Kindo, Hoang Minh Tam, Philippe Gaudard, Philippe Rouviere, Thomas Senage, Magali Michel, Aude Boignard, Olivier Chavanon, Constance Verdonk, Marylou Para, Vlad Gariboldi, Edeline Pelce, Matteo Pozzi, Jean-François Obadia, Frederic Anselme, Pierre-Yves Litzler, Gerard Babatasi, Annette Belin, Fabien Garnier, Marie Bielefeld, Julien Guihaire, Martin Kloeckner, Costin Radu, Nicolas Lellouche, Thierry Bourguignon, Thibaud Genet, Nicolas D’Ostrevy, Benjamin Duband, Jerome Jouan, Marie Cécile Bories, Fabrice Vanhuyse, Hugues Blangy, Fabrice Colas, Jean-Philippe Verhoye, Raphael Martins, Erwan Flecher On behalf of the Determination of Risk Factors of Ventricular Arrhythmias After Implantation of Continuous Flow Left Ventricular Assist Device (ASSIST-ICD) Investigators

This original article retrospectively analyzed the outcome of 671 patients undergoing LVAD implantation within the French multicenter ASSIST-ICD registry. While half of the patients were in cardiogenic shock and more than 20% of patients were on ECLS prior to implantation, the survival at five years is around 50%. This reflects the real world and all-comers nature of this registry and therefore provides a frank picture of LVAD outcomes in France between 2007 and 2017. Looking at their results, the authors recommend earlier referral of heart failure patients to lower the 50% rate of patients being in cardiogenic shock prior to implantation and thereby improving result of LVAD therapy in France.

Source: The Annals of Thoracic Surgery
Author(s): Ziyad M. Binsalamah, Christopher Ibarra, Zachary Spigel, Rodrigo Zea-Vera, Jessica Zink, Jeffrey S. Heinle, Christopher A. Caldarone

This single-center study analyzed the aortic root replacement strategies for pediatric patients from 1995 to 2018. 

Source: The New England Journal of Medicine
Author(s): Maximilian Ackermann, Stijn E. Verleden, Mark Kuehnel, Axel Haverich, Tobias Welte, Florian Laenger, Arno Vanstapel, Christopher Werlein, Helge Stark, Alexandar Tzankov, , William W. Li, Vincent W. Li, Steven J. Mentzer, Danny Jonigk

A small histopathological study of SARS and influenza autopsies compared to rejected for transplantation lungs. There is some speculation on the popular procoagulopathic nature of the panvirus, based on expression of angiotensin converting enzyme 2.There might be a collateral stimulus for lung preservation in organ retrieval.

Source: The Annals of Thoracic Surgery
Author(s): Rhami Khorfan, Timothy J. Kruser, Julia M. Coughlin, Ankit Bharat, Karl Y. Bilimoria, David D. Odell

The authors examined The National Cancer Database for patients who refused recommended surgery and elected stereotactic body radiation therapy (SBRT) for stage I/II non-small cell lung cancer. 

Source: Journal of Vascular Surgery
Author(s): Gilbert R Upchurch Jr., Guillermo C Escobar, Ali Azizzdeh, Adam W Beck, Mark F Conrad, Jon S Matsumura, Mohammad H Murad, R Jason Perry, Michael J Singh, Ravi K Veeraswamy, Grace J Wang

Upchurch and coauthors have recently published the practice guidelines on thoracic endovascular aneurysm repair (TEVAR) in the mangement of thoracic aortic aneurysms. 

Source: Journal of Cardiothoracic and Vascular Anesthesia
Author(s): Geoffrey C. Ramsdell, James A. Nelson, Sorin V. Pislaru, and Harish Ramakrishna

The authors make a brief overview of tricuspid regurgitation associated with congenital heart defects, including morphology, incidence and echocardiographic evaluation.  The status quo of medical and surgical managements and outcomes are also comprehensively reviewed.  

Source: The Annals of Thoracic Surgery
Author(s): Madhavan Ramaswamy, Yi-Ting Yeh, Riya Varman, Neil McIntosh, Denise McIntyre, Oleg Fedevych, Sachin Khambadkone, Martin Kostolny, Richard Hewitt, Nagarajan Muthialu

The authors consider simultaneous vs. staged repair of comorbid congenital tracheal stenosis in the surgical approach to these patients.

Source: Biomaterials Science
Author(s): Joanna Stasiak, Marta Serrani, Eugenia Biral, James Taylor, Azfar Zaman, Samantha Jones, Thomas Ness, Francesco de Gaetano, Maria Laura Costantino, Vito Domenico Bruno, M.-Saadeh Suleiman, Raimomdo Ascione, Geoff Moggridge

Researchers from the UK reported a novel polymeric heart valve, PoliValve, which is made entirely from styrenic block copolymers. 

The unique feature of PoliValve is that it is made of a self-assembling polymer with a microstructure conferring mechanical anisotropy analogous to that of natural valve tissue. Its prototype substantially exceeds ISO standards for in-vitro testing and shows encouraging preliminary results in acute in-vivo feasibility/safety testing in sheep without anticoagulation. Postmortem confirmed intact structure of the PHV with no evidence of any acute valvular clot/thrombus. Its durability exceeded 1.2 billion cycles in accelerated in-vitro tests, equivalent to 30 patient years. 

These results show that PoliValve is a promising alternative to traditional biological and mechanical valve prostheses, which lasts up to 30 years and does not need anticoagulation. 

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