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Journal and News Scan
This is a retrospective cohort analysis of more than 500 patients undergoing the David I procedure. They specifically looked into the outcome of 50 patients with bicuspid aortic valve undergoing this procedure. While the freedom from reoperation was not different between the two groups, the freedom from reoperation at 10 years was 79% in bicuspid valve patients. Unfortunately, the authors cannot provide markers of success for the David I procedure in patients with bicuspid valves, like geometric findings of the valve prior to reconstruction. However, these results are very encouraging for valve repair success in patients with bicuspid aortic valves.
This study assessed the association between preoperative neurologic dysfunction and postoperative neurologic injury in the diagnosis of acute type A aortic dissection.
This original article retrospectively analyzed the outcome of 671 patients undergoing LVAD implantation within the French multicenter ASSIST-ICD registry. While half of the patients were in cardiogenic shock and more than 20% of patients were on ECLS prior to implantation, the survival at five years is around 50%. This reflects the real world and all-comers nature of this registry and therefore provides a frank picture of LVAD outcomes in France between 2007 and 2017. Looking at their results, the authors recommend earlier referral of heart failure patients to lower the 50% rate of patients being in cardiogenic shock prior to implantation and thereby improving result of LVAD therapy in France.
This single-center study analyzed the aortic root replacement strategies for pediatric patients from 1995 to 2018.
A small histopathological study of SARS and influenza autopsies compared to rejected for transplantation lungs. There is some speculation on the popular procoagulopathic nature of the panvirus, based on expression of angiotensin converting enzyme 2.There might be a collateral stimulus for lung preservation in organ retrieval.
The authors examined The National Cancer Database for patients who refused recommended surgery and elected stereotactic body radiation therapy (SBRT) for stage I/II non-small cell lung cancer.
Upchurch and coauthors have recently published the practice guidelines on thoracic endovascular aneurysm repair (TEVAR) in the mangement of thoracic aortic aneurysms.
The authors make a brief overview of tricuspid regurgitation associated with congenital heart defects, including morphology, incidence and echocardiographic evaluation. The status quo of medical and surgical managements and outcomes are also comprehensively reviewed.
The authors consider simultaneous vs. staged repair of comorbid congenital tracheal stenosis in the surgical approach to these patients.
Researchers from the UK reported a novel polymeric heart valve, PoliValve, which is made entirely from styrenic block copolymers.
The unique feature of PoliValve is that it is made of a self-assembling polymer with a microstructure conferring mechanical anisotropy analogous to that of natural valve tissue. Its prototype substantially exceeds ISO standards for in-vitro testing and shows encouraging preliminary results in acute in-vivo feasibility/safety testing in sheep without anticoagulation. Postmortem confirmed intact structure of the PHV with no evidence of any acute valvular clot/thrombus. Its durability exceeded 1.2 billion cycles in accelerated in-vitro tests, equivalent to 30 patient years.
These results show that PoliValve is a promising alternative to traditional biological and mechanical valve prostheses, which lasts up to 30 years and does not need anticoagulation.