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Journal and News Scan

Source: The Journal of Thoracic and Cardiovascular Surgery
Author(s): Francis D. Pagani

Excellent and brief summary of the debate on functional mitral regurgitation on mechanical support.

Source: The New England Journal of Medicine
Author(s): Julio A. Panza, Alicia M. Ellis, Hussein R. Al-Khalidi, Thomas A. Holly, Daniel S. Berman, Jae K. Oh, Gerald M. Pohost, George Sopko, Lukasz Chrzanowski, Daniel B. Mark, Tomasz Kukulski, Liliana E. Favaloro, Gerald Maurer, Pedro S. Farsky, Ru-San Tan, Federico M. Asch, Eric J. Velazquez, Jean L. Rouleau, Kerry L. Lee, Robert O. Bonow

A robust RCT that denies association of nuclear CT-defined myocardial viability and long-term benefit from surgical coronary revascularisation. It is worth following the discussion this manuscript is certain to generate..

Source: The Annals of Thoracic Surgery
Author(s): Tara R. Semenkovich, Melanie Subramanian, Yan Yan, Wayne L. Hofstetter, Arlene M. Correa, Stephen D. Cassivi, Matthew L. Inra, Brendon M. Stiles, Nasser K. Altorki, Andrew C. Chang, Alexander A. Brescia, Gail E. Darling, Frances Allison, Stephen R. Broderick, Eric W. Etchill, Felix G. Fernandez, Ray K. Chihara, Virginia R. Litle, Juan A. Muñoz-Largacha, Benjamin D. Kozower, Varun Puri, Bryan F. Meyers

In this multiinstitutional retrospective study, administration of adjuvant chemotherapy for patients with persistent nodal disease after induction therapy and esophagectomy was associated with improved survival.

Source: Journal of Thoracic Oncology
Author(s): Daniel Shepshelovich, Wei Xu, Lin Lu, Aline Fares, Ping Yang, David Christiani, Jie Zhang, Kouya Shiraishi, Brid M. Ryan, Chu Chen, Ann G. Schwartz, Adonina Tardon, Xifeng Wu, Matthew B. Schabath, M. Dawn Teare, Loic Le Marchand, Zuo-Feng Zhang, John K. Field, Hermann Brenner, Nancy Diao, Juntao Xie, Takashi Kohno, Curtis C. Harris, Angela S. Wenzlaff, Guillermo Fernandez-Tardon, Yuanqing Ye, Fiona Taylor, Lynne R. Wilkens, Michael Davies, Yi Liu, Matt J. Barnett, Gary E. Goodman, Hal Morgenstern, Bernd Holleczek, M. Catherine Brown, Geoffrey Liu

This study of over 25,000 pts from the International Lung Cancer Consortium identified underweight and severly obese patients as having poorer survival than others, whereas a survival advantage was evident among patients who were overweight or mildly obese.  Decreased BMI (wt loss) was associated with poorer outcomes across all BMI categories.

Source: The Annals of Thoracic Surgery
Author(s): Mariko Fukui, Kenji Suzuki,Takeshi Matsunaga, Shiaki Oh, Kazuya Takamochi

An interesting discussion in this manuscript of a case-control study of 666 subjects.

Source: JAMA
Author(s): Meredith S. Duncan, Matthew S. Freiberg, Robert A. Greevy Jr, Suman Kundu, Ramachandran S. Vasan, Hilary A. Tindle

It's never too late to quit.  Among heavy smokers, smoking cessation resulted in a significantly lower risk of cardiovascular disease within five years of quitting (hazard ratio 0.61), although their risk remained elevated compared to never smokers.

Source: Journal of Thoracic Oncology
Author(s): Hyun Woo Lee, Kwang-Nam Jin , Jung-Kyu Lee, Deog Kyeom Kim, Hee Soon Chung, Eun Young Heo, Seung Ho Choi

Interesting follow-up study of 208 pulmonary ground -glass opacities in 160 subjects, with a yield of three adenocardinomas.

Source: JAMA Network Open
Author(s): James W. Suliburk, Quentin M. Buck, Chris J. Pirko, Nader N. Massarweh, Neal R. Barshes, Hardeep Singh, Todd K. Rosengart

In a QI study of nearly 5,400 operations, 188 adverse events were recorded.  Of these, over 56% were associated with human error.  Of all human performance deficiencies, cognitive error accounted for over half.

Source: JAMA Internal Medicine
Author(s): James D. Douketis, Alex C. Spyropoulos, Joanne Duncan, Marc Carrier, Gregoire Le Gal, Alfonso J. Tafur, Thomas Vanassche, Peter Verhamme, Sudeep Shivakumar, Peter L. Gross, Agnes Y. Y. Lee, Erik Yeo, Susan Solymoss, Jeannine Kassis, Geneviève Le Templier, Stephen Kowalski, Mark Blostein, Vinay Shah, Elizabeth MacKay, Cynthia Wu, Nathan P. Clark, Shannon M. Bates, Frederick A. Spencer, Eleni Arnaoutoglou, Michiel Coppens, Donald M. Arnold, Joseph A. Caprini, Na Li, Karen A. Moffat, Summer Syed, Sam Schulman

A standardized perioperative management protocol for pts taking direct oral anticoagulants for atrial fibrillation entailed no bridging with other anticoagulants.  It resulted in low and acceptable rates of major bleeding (<2%) and stroke (<1%). 

Source: Infection Control and Hospital Epidemiology
Author(s): Lili Jiang, Allison McGeer, Shelly McNeil, Kevin Katz, Mark Loeb, Matthew P. Muller, Andrew Simor, Jeff Powis, Philipp Kohler, Julia M. Di Bella, Brenda L. Coleman for the Canadian Healthcare Worker Study Group

Ever wonder why your patients get respiratory infections postoperatively? Here's another risk factor. Almost 95% of hospital caregivers completed at least one shift while ill with an acute upper respiratory infection during flu season, despite hospital policies against such behavior. This was more common among physicians than among nurses.   

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